PROCESS FOR PREPARATION OF NITROGEN MUSTARD DERIVATIVES
The present invention provides a process for the production of compound (III) or a deprotected product thereof: comprising reacting compound (II) with chloroacetic acid, in the presence of a reducing agent; wherein PG is a protecting group and R is OH in a suitably protected form or (A). The inventi...
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| Main Authors | , |
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| Format | Patent |
| Language | Chinese English |
| Published |
11.01.2019
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| Subjects | |
| Online Access | Get full text |
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| Abstract | The present invention provides a process for the production of compound (III) or a deprotected product thereof: comprising reacting compound (II) with chloroacetic acid, in the presence of a reducing agent; wherein PG is a protecting group and R is OH in a suitably protected form or (A). The invention further provides intermediate compounds formed in the process of the invention, and processes for the production of intermediate compounds. |
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| AbstractList | The present invention provides a process for the production of compound (III) or a deprotected product thereof: comprising reacting compound (II) with chloroacetic acid, in the presence of a reducing agent; wherein PG is a protecting group and R is OH in a suitably protected form or (A). The invention further provides intermediate compounds formed in the process of the invention, and processes for the production of intermediate compounds. |
| Author | WENNERBERG, Johan Anders WAHLSTRÖM, Niklas Håkan |
| Author_xml | – fullname: WAHLSTRÖM, Niklas Håkan – fullname: WENNERBERG, Johan Anders |
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| DocumentTitleAlternate | 用於製備氮芥衍生物的方法 |
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| Notes | Application Number: HK20180110180 |
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| RelatedCompanies | Oncopeptides AB |
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| Snippet | The present invention provides a process for the production of compound (III) or a deprotected product thereof: comprising reacting compound (II) with... |
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| SubjectTerms | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| Title | PROCESS FOR PREPARATION OF NITROGEN MUSTARD DERIVATIVES |
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