PROCESS FOR PREPARATION OF NITROGEN MUSTARD DERIVATIVES
The present invention provides a process for the production of compound (III) or a deprotected product thereof: comprising reacting compound (II) with chloroacetic acid, in the presence of a reducing agent; wherein PG is a protecting group and R is OH in a suitably protected form or (A). The inventi...
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Main Authors | , |
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Format | Patent |
Language | Chinese English |
Published |
11.01.2019
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Subjects | |
Online Access | Get full text |
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Abstract | The present invention provides a process for the production of compound (III) or a deprotected product thereof: comprising reacting compound (II) with chloroacetic acid, in the presence of a reducing agent; wherein PG is a protecting group and R is OH in a suitably protected form or (A). The invention further provides intermediate compounds formed in the process of the invention, and processes for the production of intermediate compounds. |
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AbstractList | The present invention provides a process for the production of compound (III) or a deprotected product thereof: comprising reacting compound (II) with chloroacetic acid, in the presence of a reducing agent; wherein PG is a protecting group and R is OH in a suitably protected form or (A). The invention further provides intermediate compounds formed in the process of the invention, and processes for the production of intermediate compounds. |
Author | WENNERBERG, Johan Anders WAHLSTRÖM, Niklas Håkan |
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DocumentTitleAlternate | 用於製備氮芥衍生物的方法 |
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RelatedCompanies | Oncopeptides AB |
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Snippet | The present invention provides a process for the production of compound (III) or a deprotected product thereof: comprising reacting compound (II) with... |
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Title | PROCESS FOR PREPARATION OF NITROGEN MUSTARD DERIVATIVES |
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