COMBINATION TUMOR TREATMENT WITH DRUG LOADED, BISPECIFIC LIGAND TARGETED MINICELLS AND INTERFERON GAMMA
Compositions and methods are provided for cancer treatments. The methodology entails, for instance, administering to a cancer patient a first composition comprising a plurality of bacterially derived intact minicells or intact killed bacterial cells, each of which encompasses an anti-neoplastic agen...
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| Main Authors | , |
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| Format | Patent |
| Language | Chinese English |
| Published |
28.07.2017
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| Subjects | |
| Online Access | Get full text |
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| Abstract | Compositions and methods are provided for cancer treatments. The methodology entails, for instance, administering to a cancer patient a first composition comprising a plurality of bacterially derived intact minicells or intact killed bacterial cells, each of which encompasses an anti-neoplastic agent and carries a bispecific ligand on the surface, the ligand having specificity for a mammalian cell component, and a second composition comprising interferon-gamma (IFN-gamma) or an agent that increases the expression of IFN-gamma in the subject. The compositions include the first composition and the second composition as described, optionally with additional anti-neoplastic agents. |
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| AbstractList | Compositions and methods are provided for cancer treatments. The methodology entails, for instance, administering to a cancer patient a first composition comprising a plurality of bacterially derived intact minicells or intact killed bacterial cells, each of which encompasses an anti-neoplastic agent and carries a bispecific ligand on the surface, the ligand having specificity for a mammalian cell component, and a second composition comprising interferon-gamma (IFN-gamma) or an agent that increases the expression of IFN-gamma in the subject. The compositions include the first composition and the second composition as described, optionally with additional anti-neoplastic agents. |
| Author | BRAHMBHATT, Himanshu MACDIARMID, Jennifer |
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| Discipline | Medicine Chemistry Sciences |
| DocumentTitleAlternate | 使用携帶藥物的、雙特異性配體靶向的微細胞和干擾素-γ的聯合腫瘤治療 |
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| Notes | Application Number: HK20160111560 |
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| RelatedCompanies | ENGENEIC MOLECULAR DELIVERY PTY LTD |
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| Snippet | Compositions and methods are provided for cancer treatments. The methodology entails, for instance, administering to a cancer patient a first composition... |
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| Title | COMBINATION TUMOR TREATMENT WITH DRUG LOADED, BISPECIFIC LIGAND TARGETED MINICELLS AND INTERFERON GAMMA |
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