SHIP1 MODULATORS AND METHODS RELATED THERETO SHIP1

• Main Authors: David BOGUCKI, Lloyd, F. MACKENZIE, Jeffery, R. RAYMOND, Thomas, B. MACRURY, Curtis HARWIG, Jeremy, D. PETTIGREW, Vladimir KHLEBNIKOV, Rudong SHAN
• Format: Patent
• Language: Chinese; English
• Published: 09.12.2016
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

n, R1, R4a, R4b, R5, R7 and R8 are defined herein, or pharmaceutically acceptable salts thereof, are described herein. The disclosed compounds have activity as SHIP1 modulators, and thus may be used to treat any of a variety of diseases, disorders or conditions that would benefit from SHIP1 modulati...