4,10-g(b)-DIACETOXY-2-g(a)-BENZOYLOXY-5-g(b),20-EPOXY-1-HYDROXY-9-OXO-19-NOR-CYCLOPROPA G]TAX-11-ENE-13-g(a)-YL (2R,3S)-TERT-BUTOXYCARBONYLAMINO-2-HYDROXY-3-PHENYLPROPIONATE DIHYDRATE, AND METHOD FOR PREPARING SAME

• Main Authors: LAVIGNE, MICHEL, DIDIER, ERIC, AUTHELIN, JEAN-RENE
• Format: Patent
• Language: English
• Published: 30.11.2001
• Edition: 7
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

A 4,10 beta -diacetoxy-2 alpha -benzoyloxy-5 beta ,20-epoxy-1-hydroxy-9-oxo-19-nor-cyclopropa[g]tax-11-ene-13 alpha -yl (2R,3S)-3-tert-butoxycarbonylamino-2-hydroxy-3-phenylpropionate dihydrate, and the preparation thereof by crystallisation from a water-alcohol or water-ketone solution, are disclos...