Particles based on polyamino-acid(s) for use as carriers for active agents and their processes of preparation

• Main Authors: SOULA, GERARD, LEMERCIER, ALAIN, HUILLE, SYLVAIN
• Format: Patent
• Language: English
• Published: 31.01.2001
• Edition: 7
• Subjects: FOODS OR FOODSTUFFS; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL; SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES

Vector particles for the admin. of active agent(s) are based on polyamino acid(s) (PAA) and of average size >200 mu m. Their PAA's comprise ≥ 2 types of recurrent amino acids NAA and IAA: NAA = hydrophobic neutral amino acid, and IAA = ionisable lateral chain amino acid; ≥ 1 part of the IAA type recurrent amino acids being in ionised form. The recurrent amino acids of each type may be the same or different and the mol.wt. of the PAA is ≥ 4000 Da (pref. ≥ 5000 Da).