PENEM DERIVATIVES, PRODUCTION AND USE THEREOF

Novel penem compounds of the formula, wherein R is hydrogen or allyl, and A is an aliphatic 5- or 6- membered heterocyclic group having one or two oxygens in the ring and their pharmaceutically acceptable salts are produced from the compounds of the formula, wherein A is as defined above and R and R...

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Bibliographic Details
Main Authors ISHIGURO, MASAJI, IWATA, HIROMITSU, TANAKA, RIE
Format Patent
LanguageEnglish
Published 30.06.1995
Edition6
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Novel penem compounds of the formula, wherein R is hydrogen or allyl, and A is an aliphatic 5- or 6- membered heterocyclic group having one or two oxygens in the ring and their pharmaceutically acceptable salts are produced from the compounds of the formula, wherein A is as defined above and R and R are respective protective groups for hydroxyl and carboxyl groups, and Z is oxygen, triarylphosphino or trialkylphosphino. The compounds and their salts are useful as antibacterial agents.
Bibliography:Application Number: GR19950400492T