Dry powder inhaler

• Main Authors: Stuart Robert Abercrombie, Marco Di Castri, Donal Joseph Taylor
• Format: Patent
• Language: English
• Published: 02.10.2024
• Subjects: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

A dry powder inhaler 1 comprising a container 7 for storing a powdered medicament, a deagglomerator 25 with a vortex chamber 26 located at an end of an inhalation channel 8 which is connected to a mouthpiece 4, and a metering device 14 comprising a shuttle 16 having a dosing recess 15. The shuttle 16 is movable between a filling position, in which the dosing recess 15 is in alignment with an opening 17 of the container 7 (Fig 2A), and an inhalation position, in which the dosing recess 15 is in alignment with the vortex chamber 26 (Fig 2C). The opening 17 of the container 7 is elongated along a major axis (Y-Y, Fig 9) and the dosing recess (15) is elongated along a main axis (X-X, Fig 9). When the shuttle 16 is in the filling position, an edge (27, Fig 9) of the opening 17 of the container 7 encloses the dosing recess 15. Also disclosed is a pharmaceutical composition, in the form of a powdered medicament suitable for administering using such an inhaler, the composition preferably comprising one or more phosphodiesterase-4 (PDE-4) inhibitors; preferably tanimilast.