PROCESS AND THE PREPARATION OF CYCLOHEXANOL DERIVATIVES
4-Trans-(N-isopropylidene-amino)-cyclohexanol of formula I by hydrolizing 4-cis/trans-acetaminocyclohexanol of formula II, and reacting the thus-obtained 4-cis/trans-aminocyclohexanol of formula III with acetone, e.g. in situ. The above compound I is an important intermediate for the preparation of...
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Main Authors | , , , , , , , , |
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Format | Patent |
Language | English |
Published |
21.07.1993
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Subjects | |
Online Access | Get full text |
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Abstract | 4-Trans-(N-isopropylidene-amino)-cyclohexanol of formula I by hydrolizing 4-cis/trans-acetaminocyclohexanol of formula II, and reacting the thus-obtained 4-cis/trans-aminocyclohexanol of formula III with acetone, e.g. in situ. The above compound I is an important intermediate for the preparation of ambroxol, which is a bronchosecretolytic agent. |
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AbstractList | 4-Trans-(N-isopropylidene-amino)-cyclohexanol of formula I by hydrolizing 4-cis/trans-acetaminocyclohexanol of formula II, and reacting the thus-obtained 4-cis/trans-aminocyclohexanol of formula III with acetone, e.g. in situ. The above compound I is an important intermediate for the preparation of ambroxol, which is a bronchosecretolytic agent. |
Author | DANIEL BOZSING ILONA SZTRUHAR GYOERGY KOVANYI ILDIKO RATZ GYOERGYI VERECZKEY PAL BENKO JOZSEF PETRO ANTAL TUNGLER TIBOR MATHE |
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Title | PROCESS AND THE PREPARATION OF CYCLOHEXANOL DERIVATIVES |
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