COMPOSES NOUVEAUX DE 1,2-ETHYLENEDIAMINE ET COMPOSITION PHARMACEUTIQUE LES CONTENANT
Compounds of the general formula I wherein R represents a halophenyl, dihalophenyl, nitrophenyl, cyanophenyl or trifluoromethylphenyl group; X represents a single bond, -CH2-, -OCH2-, SCH2, -S(O)-CH2-, -S(O)2-CH2- or -CH2CH2- R represents hydrogen or C1-3 alkyl; R represents a phenyl group substitut...
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Main Author | |
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Format | Patent |
Language | French |
Published |
30.09.1994
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Edition | 4 |
Subjects | |
Online Access | Get full text |
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Summary: | Compounds of the general formula I wherein R represents a halophenyl, dihalophenyl, nitrophenyl, cyanophenyl or trifluoromethylphenyl group; X represents a single bond, -CH2-, -OCH2-, SCH2, -S(O)-CH2-, -S(O)2-CH2- or -CH2CH2- R represents hydrogen or C1-3 alkyl; R represents a phenyl group substituted in the meta-position by a radical containing an organic base, an organic acid or a quaternary ammonium salt and optionally further substituted. R and R which may be the samme or different each represents a C3-5alkenyl, C3-5alkynyl, C1-6alkyl, or C4-7cycloalkylalkyl group, or together with the intervening nitrogen atom represents a 4-7 membered heterocyclic ring, and the pharmaceutically acceptable salts thereof are useful for the treatment of hypertension and/or inflammation in the warm-blooded animals. Also disclosed are processes for their preparation and pharmaceutical compositions containing them. |
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Bibliography: | Application Number: FR19890000705 |