1H-indoli-glyoksyyliamidi-sPLA2-inhibiittoreita

• Main Authors: DILLARD, ROBERT DELANE, BACH, NICHOLAS JAMES, DRAHEIM, SUSAN ELISABETH
• Format: Patent
• Language: Finnish; Swedish
• Published: 02.10.1995
• Edition: 6
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

A class of novel 1H-indole-3-glyoxylamides is disclosed together with the use of such indole compounds for inhibiting sPLA2 mediated release of fatty acids for treatment of conditions such as septic shock.