FOERFARANDE FOER FRAMSTAELLNING AV NYA TERAPEUTISKT ANVAENDBARA N-NITROSO-N-( -KLORETYL)KARBAMOYLPEPTIDDERIVAT
Compounds of the general Formula I [Cl-CH2-CH2-@@CO-NH]nR (I) wherein R is a group derived from any oligopeptide by removing a terminal amino group, or - if the oligopeptide comprises a diamino carboxylic acid - the amino group in the omega -position, or the terminal and omega -amino groups; and n s...
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Main Authors | , , , , , |
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Format | Patent |
Language | Finnish |
Published |
30.12.1988
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Edition | 4 |
Subjects | |
Online Access | Get full text |
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Abstract | Compounds of the general Formula I
[Cl-CH2-CH2-@@CO-NH]nR (I)
wherein
R is a group derived from any oligopeptide by removing a terminal amino group, or - if the oligopeptide comprises a diamino carboxylic acid - the amino group in the omega -position, or the terminal and omega -amino groups; and
n stands for the integral number 1 or 2
and acid addition salts thereof and a process for the preparation thereof.
The new compounds of the general Formula I exhibit antitumor activity. |
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AbstractList | Compounds of the general Formula I
[Cl-CH2-CH2-@@CO-NH]nR (I)
wherein
R is a group derived from any oligopeptide by removing a terminal amino group, or - if the oligopeptide comprises a diamino carboxylic acid - the amino group in the omega -position, or the terminal and omega -amino groups; and
n stands for the integral number 1 or 2
and acid addition salts thereof and a process for the preparation thereof.
The new compounds of the general Formula I exhibit antitumor activity. |
Author | MEDZIHRADSZKY, KALMAN MEDZIHRADSZKY NEE SCHWEIGER, HEDVIG LAPIS, KAROLY KOPPER, LASZLO SUELI NEE VARGHA, HELGA JENEY, ANDRAS |
Author_xml | – fullname: SUELI NEE VARGHA, HELGA – fullname: MEDZIHRADSZKY, KALMAN – fullname: LAPIS, KAROLY – fullname: KOPPER, LASZLO – fullname: JENEY, ANDRAS – fullname: MEDZIHRADSZKY NEE SCHWEIGER, HEDVIG |
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Edition | 4 |
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Notes | Application Number: FI19820003591 |
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RelatedCompanies | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT |
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Snippet | Compounds of the general Formula I
[Cl-CH2-CH2-@@CO-NH]nR (I)
wherein
R is a group derived from any oligopeptide by removing a terminal amino group, or - if... |
SourceID | epo |
SourceType | Open Access Repository |
SubjectTerms | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
Title | FOERFARANDE FOER FRAMSTAELLNING AV NYA TERAPEUTISKT ANVAENDBARA N-NITROSO-N-( -KLORETYL)KARBAMOYLPEPTIDDERIVAT |
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