FOERFARANDE FOER FRAMSTAELLNING AV EN NY FARMAKOLOGISKT AKTIV 1-FENYL-2-(FENOXI-ISOPROPYLAMINO)-1,3-PROPANDIOL

The invention relates to novel 1-phenyl-2-amino-1,3-propanediol-N-alkyl derivatives having the general formula I (I) wherein R1 is hydrogen, alkyl having from 1 to 8 carbon atoms or phenoxymethyl, and R2 is hydrogen, alkyl having from 1 to 8 carbon atoms or 2,2-diphenylethyl, with the proviso that i...

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Bibliographic Details
Main Authors PETOCZ LUJZA, LEVAI LASZLO, FAZEKAS GABOR, GRASSER KATALIN
Format Patent
LanguageFinnish
Published 11.03.1985
Edition4
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
APPARATUS THEREFOR
CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY
CHEMISTRY
GENERAL METHODS OF ORGANIC CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PERFORMING OPERATIONS
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
THEIR RELEVANT APPARATUS
TRANSPORTING
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Summary:The invention relates to novel 1-phenyl-2-amino-1,3-propanediol-N-alkyl derivatives having the general formula I (I) wherein R1 is hydrogen, alkyl having from 1 to 8 carbon atoms or phenoxymethyl, and R2 is hydrogen, alkyl having from 1 to 8 carbon atoms or 2,2-diphenylethyl, with the proviso that if R1 is phenoxymethyl then R2 may stand only for methyl, and if R2 is 2,2-diphenylethyl then R1 may stand only for hydrogen, and its isomers and pharmaceutically acceptable salts. Furthermore, the invention relates to a process for preparing these compounds. The novel 1-phenyl-2-amino-1,3-propanediol-N-alkyl derivatives having the general formula I possess significant anti-anginose activity and show several other biological activities.
Bibliography:Application Number: FI19780000641