Uso de derivados 2-hidroxilados de ácidos grasos poliinsaturados como medicamentos

• Main Authors: BARCELO COBLIJN, Gwendolyn, MARTIN, María Laura, ALVAREZ MARTINEZ, Rafael, LLADO CANELLAS, Victoria, TERES JIMENEZ, Silvia, BUSQUETS XAUBET, Xavier, HIGUERA URBANO, Mónica, LOPEZ, Daniel Horacio, ESCRIBA RUIZ, Pablo Vicente, MARCILLA ETXENIKE, Amaia, FERNANDEZ GARCIA, Paula, TORRES CANALEJO, Manuel, ROSELLO CASTILLO, Catalina Ana
• Format: Patent
• Language: Spanish
• Published: 19.04.2021
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; CHEMISTRY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

Compuesto, o sus sales, para uso en el tratamiento o prevención de una enfermedad, en donde dicha enfermedad se selecciona de entre el grupo que consiste en una enfermedad neurodegenerativa, una enfermedad neurológica, un desorden neuropsiquiátrico, y una enfermedad inflamatoria, en donde dicho compuesto está seleccionado entre: COOH-CHOH-(CH2)6-(CH=CH-CH2)2-(CH2)3-CH3 (182A1), COOH-CHOH-(CH2)6-(CH=CH-CH2)3-CH3 (183A1), COOH-CHOH-(CH2)3-(CH=CH-CH2)3-(CH2)3-CH3 (183A2), COOH-CHOH-(CH2)2-(CH=CH-CH2)4-(CH2)3-CH3 (204A1), COOH-CHOH-(CH2)2-(CH=CH-CH2)5-CH3 (205A1) and COOH-CHOH-CH2-(CH=CH-CH2)6-CH3 (226A1). Use of polyunsaturated fatty acid derivatives as medicaments or functional foods. The present invention relates to the use of 1,2-fatty acid derivatives in the treatment or prevention of common diseases whose etiology is based on alterations (of any type) of the cell membrane lipids, for example, changes in levels, in the composition or in the structure of these lipids. In addition, for diseases in which the regulation of lipid composition and of the structure of the membranes (or proteins that interact with membranes) causes the reversion of pathological state.