Derivados de imidazol y pirazol condensados como moduladores de la actividad de TNF

• Main Authors: CHOVATIA, Praful Tulshi, SELBY, Matthew Duncan, YULE, Ian Andrew, SHAW, Michael Alan, MILLER, Craig Adrian, DEBOVES, Hervé Jean Claude, PORTER, John Robert, BENTLEY, Jonathan Mark, KROEPLIEN, Boris, VAIDYA, Darshan Gunvant, BRACE, Gareth Neil, JONES, Elizabeth Pearl, MADDEN, James, BROOKINGS, Daniel Christopher, JOHNSTONE, Craig, ALEXANDER, Rikki Peter, LECOMTE, Fabien Claude
• Format: Patent
• Language: Spanish
• Published: 03.12.2019
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

Un compuesto de Fórmula (IIB-A), (IIB-B) o (IIB-C) o un N-óxido del mismo, o una sal o un solvato farmacéuticamente aceptables del mismo:**Fórmula** en donde A representa C-R2 o N; D representa C-R4 o N; E representa -CH2- o -CH(CH3)-; Y representa un grupo de Fórmula (Ya), (Yb), (Yc), (Yd), (Ye) o...