Brazos autorreactivos y profármacos que los comprenden

• Main Authors: PAPOT, Sébastien, THOMAS, Mickaël
• Format: Patent
• Language: Spanish
• Published: 07.05.2018
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; CHEMISTRY; DERIVATIVES THEREOF; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; NUCLEIC ACIDS; NUCLEOSIDES; NUCLEOTIDES; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SUGARS

Compuesto de fórmula general (I): en la que: - X representa OH, NH2, NHOH o R'NH con R' pudiendo representar un radical alquilo en C1 a C10, lineal o ramificado, saturado o insaturado, - Y representa un grupo electroatractor elegido entre NO2, CF3 o un halógeno, - R1 y R2 representan, independientemente uno del otro, H o un radical alquilo en C1 a C10, lineal o ramificado, saturado o insaturado, - F representa una función reactiva activable por química clic. The present invention relates to a compound of general formula (I): in which: X is OH, NH2, NHOH or RNH, where R may be a linear or branched, saturated or unsaturated, C1-C10 alkyl radical, Y is H, or an electron-withdrawing group, in particular selected from NO2, CF3 or a halogen, R1 and R2 are H or a linear or branched, saturated or unsaturated, C1-C10 alkyl radical, F is a reactive functional group that can be activated by click chemistry.