PROCEDIMIENTO PARA LA PREPARACION DE CARDESARTAN CILEXETILO EN FORMA CRISTALINA

• Main Authors: COSME GOMEZ ANTONIO, RODRIGUEZ SALGADO NATIVIDAD, PALOMO NICOLAU FRANCISCO, VICIOSO SANCHEZ MERCEDES, GONZALEZ HERNANDEZ PEDRO
• Format: Patent
• Language: Spanish
• Published: 22.12.2009
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

A process for preparing a crystalline form of candesartan cilexetil referred to as Form I, which has a content of Form II lower than 1% (w/w), is described. The process includes a seeding stage with a crystalline product, which mainly includes Form I, and a digestion stage. The invention also relate...