DERIVADOS DE PIRAZOLOPIRIDINOPIRIDAZINONAS Y PROCEDIMIENTO PARA SU PREPARACION
Nuevos derivados de pirazolpiridilpiridazinona caracterizados porque están representados por la fórmula general (1) y sus sales farmacológicamente aceptables, que presentan una actividad inhibidora de fosfodiesterasa y tienen un potente efecto selectivo de broncodilatación sobre las vías respiratori...
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Main Authors | , , , , |
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Format | Patent |
Language | Spanish |
Published |
16.06.2003
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Edition | 4 |
Subjects | |
Online Access | Get full text |
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Abstract | Nuevos derivados de pirazolpiridilpiridazinona caracterizados porque están representados por la fórmula general (1) y sus sales farmacológicamente aceptables, que presentan una actividad inhibidora de fosfodiesterasa y tienen un potente efecto selectivo de broncodilatación sobre las vías respiratorias: un procedimiento para preparar estos compuestos y broncodilatadores que los contienen como ingrediente activo: en la que R{sup,1} es un alquilo inferior C{sub,1-4} o cicloalquilo C{sub,3-6} y R{sup,2}, R{sup,3}, R{sup,4} y R{sup,5} son, independientemente, hidrógeno, alquilo o fenilo inferior C{sub,1-4}, o alternativamente R{sup,3} y R{sup,5} pueden estar unidos para formar un doble enlace.
Novel pyrazolopyridylpyridazinone derivatives characterized by being represented by general formula (1) and pharmacologically acceptable salts thereof, which exhibit a phosphodiesterase inhibiting activity and have a selective potent bronchodilating effect on the respiratory tract: a process for the preparation of them: and bronchodilators containing the same as the activity ingredient: wherein R is C1-C4 lower alkyl or C3-C6 cycloalkyl: and R , R , R and R are each independently hydrogen, C1-C4 lower alkyl or phenyl, or alternatively R and R may be united to form a double bond. |
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AbstractList | Nuevos derivados de pirazolpiridilpiridazinona caracterizados porque están representados por la fórmula general (1) y sus sales farmacológicamente aceptables, que presentan una actividad inhibidora de fosfodiesterasa y tienen un potente efecto selectivo de broncodilatación sobre las vías respiratorias: un procedimiento para preparar estos compuestos y broncodilatadores que los contienen como ingrediente activo: en la que R{sup,1} es un alquilo inferior C{sub,1-4} o cicloalquilo C{sub,3-6} y R{sup,2}, R{sup,3}, R{sup,4} y R{sup,5} son, independientemente, hidrógeno, alquilo o fenilo inferior C{sub,1-4}, o alternativamente R{sup,3} y R{sup,5} pueden estar unidos para formar un doble enlace.
Novel pyrazolopyridylpyridazinone derivatives characterized by being represented by general formula (1) and pharmacologically acceptable salts thereof, which exhibit a phosphodiesterase inhibiting activity and have a selective potent bronchodilating effect on the respiratory tract: a process for the preparation of them: and bronchodilators containing the same as the activity ingredient: wherein R is C1-C4 lower alkyl or C3-C6 cycloalkyl: and R , R , R and R are each independently hydrogen, C1-C4 lower alkyl or phenyl, or alternatively R and R may be united to form a double bond. |
Author | AWANO, KATSUYA KOUNO, YASUSHI TOORU, TAROH OGATA, TAKENOBU MATSUZAWA, KAYOKO |
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Title | DERIVADOS DE PIRAZOLOPIRIDINOPIRIDAZINONAS Y PROCEDIMIENTO PARA SU PREPARACION |
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