COMPOSICIONES ESTABILIZADAS A BASE DE FGF

• Main Authors: COURTY, JOSE, TARDIEU, MICHELE, CARUELLE, JEAN-PIERRE, JOZEFONVICZ, JACQUELINE, SLAOUI, FAOUZI, BARRITAULT, DENIS
• Format: Patent
• Language: Spanish
• Published: 16.10.1994
• Edition: 4
• Subjects: CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES; CHEMISTRY; COMPOSITIONS BASED THEREON; DERIVATIVES THEREOF; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; HUMAN NECESSITIES; HYGIENE; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES; MEDICAL OR VETERINARY SCIENCE; METALLURGY; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL; ORGANIC MACROMOLECULAR COMPOUNDS; POLYSACCHARIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; THEIR PREPARATION OR CHEMICAL WORKING-UP

AGENTES CON ACTIVIDAD REGENERADORA CELULAR Y DE LOS TEJIDOS CONSTITUIDOS POR DEXTRANOS SUSTITUIDOS FUNCIONALIZADOS, COMPOSICIONES QUE CONTIENEN DICHOS AGENTES ASOCIADOS A AL MENOS UN FACTOR DE CRECIMIENTO DE LOS FIBROBLASTOS (FGFS) TAL COMO UN FGF ACIDO Y/O UN FGF BASICO Y/O UN DERIVADO Y/O UN ANALOGO Y/O UN FRAGMENTO DE ESTOS QUE PRESENTA UNA ACTIVIDAD BIOLOGICA Y SUS APLICACIONES IN VITRO TALES COMO ALMACENAMIENTO DE LOS FGFS Y LOS CULTIVOS CELULARES Y APLICACIONES IN VITRO COMO AGENTE TERAPEUTICO, EN PARTICULAR PARA LA CICATRIZACION Y LA REGENERACION DE LOS TEJIDOS O COMO AGENTE COSMETICO. Agents having a cellular and tissular regenerating activity consisting of functionalized substituted dextrans, stabilized compositions containing said agents associated with at least one fibroblast growth factor (FGFs) such as a FGF acid and/or a basic FGF and/or a derivative and/or an analogue and/or a fragment of these disclosing a biological activity and their $i(in vitro) applications such as storing FGFs and cellular cultures and $i(in vivo) applications as a therapeutic agent, in particular for healing and tissular regeneration or as a cosmetic agent.