PREPARADO DE TIPO DE ABSORCION PERCUTANEA Y PROCEDIMIENTO DE SU PREPARACION

• Main Authors: ITO, YUUSUKE CNO NITTO DENKO CORPORATION, SHIBATA, KEISUKE CNO NITTO DENKO CORPORATION, TOKUDA, SHOICHI CNO NITTO DENKO CORPORATION, KINOSHITA, TAKASHI CNO NITTO DENKO CORPORATION, OTSUKA, SABURO CNO NITTO DENKO CORPORATION
• Format: Patent
• Language: Spanish
• Published: 16.01.1994
• Edition: 4
• Subjects: CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; HUMAN NECESSITIES; HYGIENE; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES; MEDICAL OR VETERINARY SCIENCE; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

SE DESCRIBE UNA PREPARACION TIPO PARA ABSORCION PERCUTANEA Y UN PROCEDIMIENTO PARA PREPARARLA. LA PREPARACION COMPRENDE UN APOYO SUSTANCIALMENTE IMPERMEABLE AL MEDICAMENTO, QUE TIENE SOBRE EL UNA CAPA ADHESIVA, QUE COMPRENDE UN ADHESIVO SENSIBLE A LA PRESION, QUE CONTIENE UN MEDICAMENTO TIPO PARA ABSORCION PERCUTANEA (SOLIDO A TEMPERATURA AMBIENTE) EN CANTIDAD MAYOR QUE LA SOLUBILIDAD EN EL ADHESIVO SATURADO, DONDE LA CANTIDAD EN EXCESO DE MEDICAMENTO MAYOR QUE LA SOLUBILIDAD DE SATURACION SE HALLA EN EL ADHESIVO EN ESTADO CRISTALIZADO CONTINUO Y EN ESTADO SUSTANCIALMENTE RETICULAR A percutaneous absorption type preparation and a process for preparing the same are disclosed. The preparation comprises a substantially drug-impermeable backing having provided thereon an adhesive layer comprising a pressure-sensitive adhesive containing therein a percutaneous absorption type drug (solid at room temperature) in an amount greater than the saturated solubility in the adhesive, wherein the excess amount of the drug greater than the saturated solubility is present in the adhesive in a continuous recrystallized state and a substantially network state.