CRF2 RECEPTOR AGONISTS AND THEIR USE IN THERAPY

The present disclosure provides compounds which are peptides comprising the amino acid sequence of the formula (I) disclosed herein or pharmaceutically acceptable salts thereof. The compounds act as agonists of the corticotropin-releasing factor receptor 2 (CRF2) and are useful in therapy, especiall...

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Main Authors ROVERSI, Daniela, LUCATS, Laurence, ILLIANO, Stephane, TRIPEPI, Martina, OZOUX, Marie-Laure, BIANCHI, Elisabetta, LEDEIN, Laetitia, EVERS, Andreas, BEAUVERGER, Philippe, JANIAK, Philip, ELVERT, Ralf, HALLAND, Nis, LI, Ziyu
Format Patent
LanguageEnglish
French
German
Published 25.09.2024
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Summary:The present disclosure provides compounds which are peptides comprising the amino acid sequence of the formula (I) disclosed herein or pharmaceutically acceptable salts thereof. The compounds act as agonists of the corticotropin-releasing factor receptor 2 (CRF2) and are useful in therapy, especially in the treatment or prevention of cardiovascular diseases, obesity and diabetes.
Bibliography:Application Number: EP20240179173