COMPOSITIONS COMPRISING NKG2D, CXCR2, AND DAP10/DAP12 FUSION POLYPEPTIDES AND METHODS OF USE THEREOF
Immunoresponsive cells comprising an NKG2D polypeptide and a CXCR2 polypeptide, and, optionally, a fusion polypeptide comprising a DNAX-activating 10 (DAP10) polypeptide and a DNAX-activating protein 12 (DAP12) polypeptide, are provided. Also provided are methods of making and using such immunorespo...
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Format | Patent |
Language | English French German |
Published |
28.08.2024
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Abstract | Immunoresponsive cells comprising an NKG2D polypeptide and a CXCR2 polypeptide, and, optionally, a fusion polypeptide comprising a DNAX-activating 10 (DAP10) polypeptide and a DNAX-activating protein 12 (DAP12) polypeptide, are provided. Also provided are methods of making and using such immunoresponsive cells. |
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AbstractList | Immunoresponsive cells comprising an NKG2D polypeptide and a CXCR2 polypeptide, and, optionally, a fusion polypeptide comprising a DNAX-activating 10 (DAP10) polypeptide and a DNAX-activating protein 12 (DAP12) polypeptide, are provided. Also provided are methods of making and using such immunoresponsive cells. |
Author | MAHER, John DAVIES, David Marc LACOMB-YOUNG, Daniel |
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DocumentTitleAlternate | COMPOSITIONS COMPRENANT DES POLYPEPTIDES DE FUSION NKG2D, CXCR2, ET DAP10/DAP12 ET LEURS PROCÉDÉS D'UTILISATION ZUSAMMENSETZUNGEN MIT NKG2D, CXCR2 UND DAP10/DAP12 FUSIONSPOLYPEPTIDEN UND VERFAHREN ZUR VERWENDUNG DAVON |
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Title | COMPOSITIONS COMPRISING NKG2D, CXCR2, AND DAP10/DAP12 FUSION POLYPEPTIDES AND METHODS OF USE THEREOF |
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