2-AMINO-5,5-DIMETHYLHEXANOIC ACID DERIVATIVES AS SORTILIN MODULATORS FOR USE IN THE TREATMENT OF DISEASE OF THE CENTRAL NERVOUS SYSTEM
The present invention relates to a compound that binds to and modulates the activity of sortilin, wherein the compound has a blood-to-brain Kpuu greater than 0.1. The compounds are capable of crossing the blood brain barrier and are suitable for use in the treatment of a disease of the central nervo...
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Main Authors | , , , |
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Format | Patent |
Language | English French German |
Published |
10.07.2024
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Subjects | |
Online Access | Get full text |
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