METHOD FOR PREPARING A LIBRARY OF PEPTIDES OR A PEPTIDE

• Main Authors: SANGOUARD, Gontran, MERZ, Manuel, SCHÜTTEL, Mischa, BOGNÁR, Zsolt, HEINIS, Christian, HABESHIAN, Sevan, MOTHUKURI, Ganesh Kumar, NIELSEN, Alexander Lund
• Format: Patent
• Language: English; French; German
• Published: 27.03.2024
• Subjects: CHEMISTRY; COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES

The present invention relates to a method for preparing a library of peptides or an isolated peptide comprising (a) releasing one or more linear dithiol peptides carrying a sulfhydryl group in the N-terminal region of the one or more peptides and being immobilized via a disulfide bridge in the C-ter...