BIFUNCTIONAL DEGRADERS OF GALACTOSE-DEFICIENT IMMUNOGLOBULINS
An agent including a glycan-specific IgG antibody moiety, a cellular receptor binding moiety which binds to hepatocytes or other degrading cells through asialoglycoprotein (ASGPR) receptors of hepatocytes or other cell receptors which are on the surface degrading cells in a patient or subject, and o...
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Main Authors | , , |
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Format | Patent |
Language | English French German |
Published |
17.01.2024
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Online Access | Get full text |
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Abstract | An agent including a glycan-specific IgG antibody moiety, a cellular receptor binding moiety which binds to hepatocytes or other degrading cells through asialoglycoprotein (ASGPR) receptors of hepatocytes or other cell receptors which are on the surface degrading cells in a patient or subject, and optionally, a linker moiety connecting the glycan-specific IgG antibody moiety and the cellular receptor binding moiety. |
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AbstractList | An agent including a glycan-specific IgG antibody moiety, a cellular receptor binding moiety which binds to hepatocytes or other degrading cells through asialoglycoprotein (ASGPR) receptors of hepatocytes or other cell receptors which are on the surface degrading cells in a patient or subject, and optionally, a linker moiety connecting the glycan-specific IgG antibody moiety and the cellular receptor binding moiety. |
Author | SPIEGEL, David CALDWELL, Reese M DUBOWCHIK, Gene M |
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DocumentTitleAlternate | BIFUNKTIONELLE DEGRADER VON IMMUNGLOBULINEN MIT DEFIZIENTER GALACTOSE AGENTS DE DÉGRADATION BIFONCTIONNELS D'IMMUNOGLOBULINES DÉFICIENTES EN GALACTOSE |
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RelatedCompanies | Biohaven Therapeutics Ltd |
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Snippet | An agent including a glycan-specific IgG antibody moiety, a cellular receptor binding moiety which binds to hepatocytes or other degrading cells through... |
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SubjectTerms | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
Title | BIFUNCTIONAL DEGRADERS OF GALACTOSE-DEFICIENT IMMUNOGLOBULINS |
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