ADENOSINE DERIVATIVE HAVING ANTAGONISTIC ACTION ON A2A AND A3 ADENOSINE RECEPTORS AND METHOD FOR PREPARING SAME
The present invention relates to: an adenosine derivative capable of acting as an antagonist on A2A and A3 adenosine receptors through the introduction of substituents into the 2nd and 8th carbons and 6th and/or 9th amine(s); a pharmaceutical composition including the same; and a method for preparin...
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Format | Patent |
Language | English French German |
Published |
09.10.2024
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Abstract | The present invention relates to: an adenosine derivative capable of acting as an antagonist on A2A and A3 adenosine receptors through the introduction of substituents into the 2nd and 8th carbons and 6th and/or 9th amine(s); a pharmaceutical composition including the same; and a method for preparing the same. The adenosine derivative regulates the activity of an A2A or A3 adenosine receptor, and thus can effectively prevent or treat brain diseases, cardiovascular diseases, sleep disorders, inflammation, immune system diseases and the like in which the receptors are involved. |
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AbstractList | The present invention relates to: an adenosine derivative capable of acting as an antagonist on A2A and A3 adenosine receptors through the introduction of substituents into the 2nd and 8th carbons and 6th and/or 9th amine(s); a pharmaceutical composition including the same; and a method for preparing the same. The adenosine derivative regulates the activity of an A2A or A3 adenosine receptor, and thus can effectively prevent or treat brain diseases, cardiovascular diseases, sleep disorders, inflammation, immune system diseases and the like in which the receptors are involved. |
Author | CHOI, Jong Ryoul JANG, Hyu Jeong LEE, Hyuk Woo JI, Seung Hee KIM, Ji Won KIM, Seo Hyun KANG, Ji Yoon SON, Seo Hyun AHN, Sang Yeop BYUN, Joon Seok |
Author_xml | – fullname: LEE, Hyuk Woo – fullname: KIM, Ji Won – fullname: KIM, Seo Hyun – fullname: CHOI, Jong Ryoul – fullname: JANG, Hyu Jeong – fullname: BYUN, Joon Seok – fullname: AHN, Sang Yeop – fullname: KANG, Ji Yoon – fullname: JI, Seung Hee – fullname: SON, Seo Hyun |
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DocumentTitleAlternate | DÉRIVÉ D'ADÉNOSINE AYANT UNE ACTION ANTAGONISTE SUR LES RÉCEPTEURS DE L'ADÉNOSINE A2A ET A3 ET PROCÉDÉ DE PRÉPARATION ASSOCIÉ ADENOSINDERIVAT MIT ANTAGONISTISCHER WIRKUNG AUF A2A- UND A3-ADENOSINREZEPTOREN UND VERFAHREN ZUR HERSTELLUNG DAVON |
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Snippet | The present invention relates to: an adenosine derivative capable of acting as an antagonist on A2A and A3 adenosine receptors through the introduction of... |
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SubjectTerms | CHEMISTRY DERIVATIVES THEREOF HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SUGARS |
Title | ADENOSINE DERIVATIVE HAVING ANTAGONISTIC ACTION ON A2A AND A3 ADENOSINE RECEPTORS AND METHOD FOR PREPARING SAME |
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