PROCESS FOR THE PREPARATION OF ILOPROST

• Main Authors: SZABÓ, Tibor, KARDOS, Zsuzsanna, ROZSUMBERSZKI, Imre, VÁRADI, Csaba, BÁN, Tamás, HORTOBÁGYI, Irén
• Format: Patent
• Language: English; French; German
• Published: 27.12.2023
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; CHEMISTRY; METALLURGY; ORGANIC CHEMISTRY

The present invention relates to a process for the preparation of iloprost of formula I through new intermediates, isolation of iloprost of formula I in solid form, as well as preparation of the 16(5)-iloprost and 16(R)-iloprost isomers of formulae (S)-I and (R)-I and isolation of iloprost of formul...