MRGX2 ANTAGONISTS

This invention relates to novel compounds according to Formula (I) which are antagonists of MrgX2, to pharmaceutical compositions containing them, and to their use in therapy for the treatment of MrgX2-mediated diseases and disorders.

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Main Authors PAONE, Daniel, BURY, Michael, YING, Maben, SHEARER, Barry, COLLINS, Jon, BRNARDIC, Edward, LAMBERT, Millard, Hurst, III, LI, Yue, ZHANG, Huichang, HANDLON, Anthony, LI, Huijie, SCHULTE, Christie, GUO, Yu, CADILLA, Rodolfo, YE, Guosen
Format Patent
LanguageEnglish
French
German
Published 16.08.2023
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Abstract This invention relates to novel compounds according to Formula (I) which are antagonists of MrgX2, to pharmaceutical compositions containing them, and to their use in therapy for the treatment of MrgX2-mediated diseases and disorders.
AbstractList This invention relates to novel compounds according to Formula (I) which are antagonists of MrgX2, to pharmaceutical compositions containing them, and to their use in therapy for the treatment of MrgX2-mediated diseases and disorders.
Author YING, Maben
CADILLA, Rodolfo
GUO, Yu
PAONE, Daniel
BRNARDIC, Edward
LI, Huijie
SHEARER, Barry
SCHULTE, Christie
YE, Guosen
COLLINS, Jon
ZHANG, Huichang
LAMBERT, Millard, Hurst, III
HANDLON, Anthony
BURY, Michael
LI, Yue
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– fullname: YING, Maben
– fullname: SHEARER, Barry
– fullname: COLLINS, Jon
– fullname: BRNARDIC, Edward
– fullname: LAMBERT, Millard, Hurst, III
– fullname: LI, Yue
– fullname: ZHANG, Huichang
– fullname: HANDLON, Anthony
– fullname: LI, Huijie
– fullname: SCHULTE, Christie
– fullname: GUO, Yu
– fullname: CADILLA, Rodolfo
– fullname: YE, Guosen
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DocumentTitleAlternate MRGX2-ANTAGONISTEN
ANTAGONISTES DE MRGX2
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Snippet This invention relates to novel compounds according to Formula (I) which are antagonists of MrgX2, to pharmaceutical compositions containing them, and to their...
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SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title MRGX2 ANTAGONISTS
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