SOLUTE-PHASE ELECTROCHEMICAL APTAMER SENSORS FOR IMPROVED LONGEVITY AND SENSITIVITY

A device and method for detecting the presence of, or measuring the concentration or amount of, at least one analyte in a sample fluid. The device 100 includes at least one electrode 150, a sensor fluid 18, a plurality of aptamers freely diffusing in the sensor fluid, and a plurality of redox tags a...

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Bibliographic Details
Main Authors HEIKENFELD, Jason, YUAN, Yuchan
Format Patent
LanguageEnglish
French
German
Published 02.08.2023
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Summary:A device and method for detecting the presence of, or measuring the concentration or amount of, at least one analyte in a sample fluid. The device 100 includes at least one electrode 150, a sensor fluid 18, a plurality of aptamers freely diffusing in the sensor fluid, and a plurality of redox tags associated with at least a subset of aptamers of the plurality of aptamers. The sensor fluid is capable of having a sample fluid 14 introduced thereinto, and the detection or measurement of any analyte may occur through a change in electron transfer from at least one redox tag of the plurality of redox tags.
Bibliography:Application Number: EP20210873476