MULTI-SPECIFIC ANTIGEN BINDING MOLECULES TARGETING HIV AND METHODS OF USE

Provided are multi-specific antigen binding molecules, including bispecific antibodies, that bind to CD3 and an HIV antigen, including HIV envelope protein gp120. Also provided are methods of using such antigen binding molecules to treat or prevent HIV infection.

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Main Authors BACA, Manuel, GOLDSMITH, Joshua, BLAIR, Wade S, STEPHENSON, Heather T, PAN, YenRu, THOMSEN, Nathan D, HUNG, Magdeleine S, NAGEL, Mark, CLANCY, Sheila B, KANWAR, Manu, CARR, Brian A, MOLDT, Brian, PACE, Craig S
Format Patent
LanguageEnglish
French
German
Published 05.07.2023
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Abstract Provided are multi-specific antigen binding molecules, including bispecific antibodies, that bind to CD3 and an HIV antigen, including HIV envelope protein gp120. Also provided are methods of using such antigen binding molecules to treat or prevent HIV infection.
AbstractList Provided are multi-specific antigen binding molecules, including bispecific antibodies, that bind to CD3 and an HIV antigen, including HIV envelope protein gp120. Also provided are methods of using such antigen binding molecules to treat or prevent HIV infection.
Author HUNG, Magdeleine S
PAN, YenRu
CLANCY, Sheila B
GOLDSMITH, Joshua
NAGEL, Mark
THOMSEN, Nathan D
STEPHENSON, Heather T
BACA, Manuel
PACE, Craig S
KANWAR, Manu
BLAIR, Wade S
CARR, Brian A
MOLDT, Brian
Author_xml – fullname: BACA, Manuel
– fullname: GOLDSMITH, Joshua
– fullname: BLAIR, Wade S
– fullname: STEPHENSON, Heather T
– fullname: PAN, YenRu
– fullname: THOMSEN, Nathan D
– fullname: HUNG, Magdeleine S
– fullname: NAGEL, Mark
– fullname: CLANCY, Sheila B
– fullname: KANWAR, Manu
– fullname: CARR, Brian A
– fullname: MOLDT, Brian
– fullname: PACE, Craig S
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DocumentTitleAlternate GEGEN HIV GERICHTETE MULTISPEZIFISCHE ANTIGENBINDENDE MOLEKÜLE UND VERFAHREN ZUR VERWENDUNG
MOLÉCULES DE LIAISON À UN ANTIGÈNE MULTI-SPÉCIFIQUES CIBLANT LE VIH ET MÉTHODES D'UTILISATION
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Snippet Provided are multi-specific antigen binding molecules, including bispecific antibodies, that bind to CD3 and an HIV antigen, including HIV envelope protein...
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SubjectTerms CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title MULTI-SPECIFIC ANTIGEN BINDING MOLECULES TARGETING HIV AND METHODS OF USE
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