PARAMETRIC MODELING AND INFERENCE OF DIAGNOSTICALLY RELEVANT HISTOLOGICAL PATTERNS IN DIGITIZED TISSUE IMAGES
A computational pathology method includes receiving multi-parameter cellular and/or sub-cellular imaging data for an image of a tissue sample, and locating and segmenting a plurality of tissue components of the tissue sample in the multi- parameter cellular and sub-cellular imaging data to generate...
Saved in:
Main Authors | , , |
---|---|
Format | Patent |
Language | English French German |
Published |
14.08.2024
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | A computational pathology method includes receiving multi-parameter cellular and/or sub-cellular imaging data for an image of a tissue sample, and locating and segmenting a plurality of tissue components of the tissue sample in the multi- parameter cellular and sub-cellular imaging data to generate segmented multi¬ parameter cellular and sub-cellular imaging data. The method further includes applying a parametric feature modelling scheme to certain of the tissue components in the segmented multi-parameter cellular and sub-cellular imaging data, wherein the parametric feature modelling scheme is generated from a dictionary of pre-existing diagnostically relevant histological patterns and comprises a number of structural features adapted for defining a number of disease entities of a disease, and wherein the applying includes determining a quantification of each of the structural features for the tissue sample, and classifying a state of the disease in the tissue sample based the determined quantification of each of the structural features. |
---|---|
AbstractList | A computational pathology method includes receiving multi-parameter cellular and/or sub-cellular imaging data for an image of a tissue sample, and locating and segmenting a plurality of tissue components of the tissue sample in the multi- parameter cellular and sub-cellular imaging data to generate segmented multi¬ parameter cellular and sub-cellular imaging data. The method further includes applying a parametric feature modelling scheme to certain of the tissue components in the segmented multi-parameter cellular and sub-cellular imaging data, wherein the parametric feature modelling scheme is generated from a dictionary of pre-existing diagnostically relevant histological patterns and comprises a number of structural features adapted for defining a number of disease entities of a disease, and wherein the applying includes determining a quantification of each of the structural features for the tissue sample, and classifying a state of the disease in the tissue sample based the determined quantification of each of the structural features. |
Author | CHENNUBHOTLA, Srinivas C TOSUN, Akif Burak FINE, Jeffrey |
Author_xml | – fullname: TOSUN, Akif Burak – fullname: CHENNUBHOTLA, Srinivas C – fullname: FINE, Jeffrey |
BookMark | eNqNi0sKwjAQQLvQhb87zAVciAXpckim6UCalGQUdFOKxJW2hXp_rOABXD14vLfOFv3Qp1X2ajBgTRJYQe01WXYG0GlgV1Igpwh8CZrROB-FFVp7hUCWLugEKo7irTdfDw2KUHBxXufBsPCNNAjHeCbgGg3FbbZ8dM8p7X7cZFCSqGqfxqFN09jdU5_eLTX54VTkRYH58Y_kAz_kOLY |
ContentType | Patent |
DBID | EVB |
DatabaseName | esp@cenet |
DatabaseTitleList | |
Database_xml | – sequence: 1 dbid: EVB name: esp@cenet url: http://worldwide.espacenet.com/singleLineSearch?locale=en_EP sourceTypes: Open Access Repository |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Medicine Chemistry Sciences Physics |
DocumentTitleAlternate | PARAMETRISCHE MODELLIERUNG UND INFERENZ VON DIAGNOSTISCH RELEVANTEN HISTOLOGISCHEN MUSTERN IN DIGITALISIERTEN GEWEBEBILDERN MODÉLISATION PARAMÉTRIQUE ET INFÉRENCE DE MOTIFS HISTOLOGIQUES PERTINENTS POUR LE DIAGNOSTIC DANS DES IMAGES DE TISSU NUMÉRISÉES |
ExternalDocumentID | EP4179499A4 |
GroupedDBID | EVB |
ID | FETCH-epo_espacenet_EP4179499A43 |
IEDL.DBID | EVB |
IngestDate | Fri Aug 23 06:55:05 EDT 2024 |
IsOpenAccess | true |
IsPeerReviewed | false |
IsScholarly | false |
Language | English French German |
LinkModel | DirectLink |
MergedId | FETCHMERGED-epo_espacenet_EP4179499A43 |
Notes | Application Number: EP20210838666 |
OpenAccessLink | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240814&DB=EPODOC&CC=EP&NR=4179499A4 |
ParticipantIDs | epo_espacenet_EP4179499A4 |
PublicationCentury | 2000 |
PublicationDate | 20240814 |
PublicationDateYYYYMMDD | 2024-08-14 |
PublicationDate_xml | – month: 08 year: 2024 text: 20240814 day: 14 |
PublicationDecade | 2020 |
PublicationYear | 2024 |
RelatedCompanies | University of Pittsburgh - of the Commonwealth System of Higher Education |
RelatedCompanies_xml | – name: University of Pittsburgh - of the Commonwealth System of Higher Education |
Score | 3.5644064 |
Snippet | A computational pathology method includes receiving multi-parameter cellular and/or sub-cellular imaging data for an image of a tissue sample, and locating and... |
SourceID | epo |
SourceType | Open Access Repository |
SubjectTerms | CALCULATING COMPUTING COUNTING IMAGE DATA PROCESSING OR GENERATION, IN GENERAL PHYSICS |
Title | PARAMETRIC MODELING AND INFERENCE OF DIAGNOSTICALLY RELEVANT HISTOLOGICAL PATTERNS IN DIGITIZED TISSUE IMAGES |
URI | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240814&DB=EPODOC&locale=&CC=EP&NR=4179499A4 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3dT8IwEL8gfr4pasSv9MHsbTGDsuEDMWXtRg37yFYI-mK2MRMeBCIz_vu2DaAv-tZcc016yfV-vfZ-B3BnO4XVKi1syjty28Tttwczx53MxNMskxEm61qa8SYI7cEIP006kxrMNrUwmif0S5MjSo8qpL9X-rxe_iSxqP5bubrPZ1K0ePREjxrr27Hi67KwQfs9Fkc0cg3XlSMjTHqq0ZYE9wTvwK5C0Ypmn437qihl-TuieMewF8vF5tUJ1Mp5Aw7dTeO1BhwE6_fuBuzrD5rFSgrXTrg6hfeYJCRgIuEuCiLKhjz0EQkp4qHHEpUyQpGHKCd-GKVC8R0Mn1HChmxMQoEGPBWbDggoJkIx4qZSVSr4XPAXRpHgaTpiiAfEZ-kZII8Jd2DKHbxurfXK4u1e2-dQny_m5QWglgTRGGtyewdnudWdZrZErJ1uUViOY5dNaP65zOU_c1dwpMyusqwWvoZ69fFZ3sgwXeW32sDf-LKNKg |
link.rule.ids | 230,309,786,891,25594,76903 |
linkProvider | European Patent Office |
linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1LT8JAEJ4gPvCmqBGfezC9NaawUDwQU9ptu9pX2oWgF9KWmnAQiGD8-043gF70tpnNbjK7mZ3HznwDcNfRc61ZaFRFH7ml0tbbg5rRdqrSSZqihkm7mkS88YOOO6BPo_aoAtNNLYzECf2S4IgoUTnK-0q-14ufIJYlcyuX99kUSfNHW_QsZe0dl3hdGlWsfo9FoRWaimniSAniXtloC417g-7Aro4eofSUhv2yKGXxW6PYR7AX4Waz1TFUilkdauam8VodDvz1f3cd9mWCZr5E4loIlyfwHhmx4TMRc5P4ocU8HjjECCzCA5vFZciIhDaxuOEEYSJKvAPvhcTMY0MjEMTlidh0QCCRIUpE3ASX4gKHC_7KLCJ4kgwY4b7hsOQUiM2E6arIwXh7WmMWbXltnUF1Np8V50CaaERTKsHtdZpmWneSdtBibXfzXNP1TtGAxp_bXPwzdws1V_jeGFl9voTD8grKiKtGr6C6-vgsrlFlr7Ibedjft7OQFA |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Apatent&rft.title=PARAMETRIC+MODELING+AND+INFERENCE+OF+DIAGNOSTICALLY+RELEVANT+HISTOLOGICAL+PATTERNS+IN+DIGITIZED+TISSUE+IMAGES&rft.inventor=TOSUN%2C+Akif+Burak&rft.inventor=CHENNUBHOTLA%2C+Srinivas+C&rft.inventor=FINE%2C+Jeffrey&rft.date=2024-08-14&rft.externalDBID=A4&rft.externalDocID=EP4179499A4 |