TREATMENT WITH ANTI-TIGIT ANTIBODIES AND PD-1 AXIS BINDING ANTAGONISTS
The present invention relates to the treatment of esophageal cancer, e.g., esophageal squamous cell carcinoma (ESCC) (e.g., advanced ESCC (e.g., unresectable, locally advanced, recurrent, and/or metastatic ESCC)). More specifically, the invention pertains to the treatment of patients having esophage...
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| Main Authors | , , , , |
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| Format | Patent |
| Language | English French German |
| Published |
26.04.2023
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| Subjects | |
| Online Access | Get full text |
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| Abstract | The present invention relates to the treatment of esophageal cancer, e.g., esophageal squamous cell carcinoma (ESCC) (e.g., advanced ESCC (e.g., unresectable, locally advanced, recurrent, and/or metastatic ESCC)). More specifically, the invention pertains to the treatment of patients having esophageal cancer by administering a combination of an anti-T-cell immunoreceptor with Ig and ITIM domains (TIGIT) antagonist antibody and a programmed death-1 (PD-1) axis binding antagonist. |
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| AbstractList | The present invention relates to the treatment of esophageal cancer, e.g., esophageal squamous cell carcinoma (ESCC) (e.g., advanced ESCC (e.g., unresectable, locally advanced, recurrent, and/or metastatic ESCC)). More specifically, the invention pertains to the treatment of patients having esophageal cancer by administering a combination of an anti-T-cell immunoreceptor with Ig and ITIM domains (TIGIT) antagonist antibody and a programmed death-1 (PD-1) axis binding antagonist. |
| Author | LI, Shi CHA, Edward, Namserk WANG, Yifan GE, Feijiao HARRIS, Meghna, Das Thakur |
| Author_xml | – fullname: HARRIS, Meghna, Das Thakur – fullname: GE, Feijiao – fullname: LI, Shi – fullname: CHA, Edward, Namserk – fullname: WANG, Yifan |
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| DocumentTitleAlternate | BEHANDLUNG MIT ANTI-TIGIT-ANTIKÖRPERN UND PD-1-ACHSEN-BINDENDEN ANTAGONISTEN TRAITEMENT AVEC DES ANTICORPS ANTI-TIGIT ET DES ANTAGONISTES DE LIAISON À L'AXE PD-1 |
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| Notes | Application Number: EP20210706122 |
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| PublicationDateYYYYMMDD | 2023-04-26 |
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| RelatedCompanies | GENENTECH, INC F. Hoffmann-La Roche AG |
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| Snippet | The present invention relates to the treatment of esophageal cancer, e.g., esophageal squamous cell carcinoma (ESCC) (e.g., advanced ESCC (e.g., unresectable,... |
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| Title | TREATMENT WITH ANTI-TIGIT ANTIBODIES AND PD-1 AXIS BINDING ANTAGONISTS |
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