COMPOSITIONS AND METHODS FOR TREATING CANCER EXPRESSING CD90 AND CD326

• Main Authors: MARTINEZ-OSUNA, Manuel, KOLLET, Jutta, ECKARDT, Dominik, DITTMER, Vera, HERBEL, Christoph, HARDT, Olaf, Thorsten, BOSIO, Andreas
• Format: Patent
• Language: English; French; German
• Published: 29.03.2023
• Subjects: CHEMISTRY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

The present invention provides a combination comprising a) an antigen binding domain specific for CD90, and b) an antigen binding domain specific for CD326, for use in treatment of human cancer comprising cancerous cells that co-express CD90 and CD326. In one embodiment of the invention the combinat...