RAPID SINGLE-STEP GRADIENT METHOD FOR THE GENERATION OF NANOANTIBODIES

• Main Authors: LÓPEZ, Natalia, SALINAS, Constanza, PINTO, Teresa, CHEUQUEMILLA, Yorka, UBERTI, Benjamín, JARA, Ronald, MULLER, Ananda, VALENZUELA, Guillermo, HIMELREICHS, Johanna, CUEVAS, Alexei, ROJAS, Alejandro, MIRANDA, Zaray
• Format: Patent
• Language: English; French; German
• Published: 22.03.2023
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMBINATORIAL CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES; MEASURING; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PHYSICS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; TESTING; VINEGAR; WINE

One-step rapid gradient method for rapid generation of nanoantibodies (HHV) against any antigen. Where the method comprises the separation of nanoantibodies against a specific antigen from a nanoantibody expression library through the following steps:(a) binding the antigen of interest to beads made...