DIFLUOROCYCLOHEXYL DERIVATIVES AS IL-17 MODULATORS

A series of substituted 4,4-difluorocyclohexyl derivatives as defined herein, being potent modulators of human IL-17 activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including inflammatory and autoimmune disorders.

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Bibliographic Details
Main Authors HASLETT, Gregory William, HUTCHINGS, Martin Clive, QUINCEY, Joanna Rachel, VAIDYA, Darshan Gunvant, MONCK, Nathaniel Julius Thomas, JOHNSON, James Andrew, CHOVATIA, Prafulkumar Tulshibhai, SMALLEY, Adam Peter, FOLEY, Anne Marie, TRANI, Giancarlo, REUBERSON, James Thomas, LECOMTE, Fabien Claude, RAMPALAKOS, Konstantinos
Format Patent
LanguageEnglish
French
German
Published 15.02.2023
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:A series of substituted 4,4-difluorocyclohexyl derivatives as defined herein, being potent modulators of human IL-17 activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including inflammatory and autoimmune disorders.
Bibliography:Application Number: EP20210717399