PHARMACEUTICAL COMPOSITIONS COMPRISING DASATINIB ANHYDROUS AND USES THEREOF

Pharmaceutical compositions comprising dasatinib anhydrous provide an improved, pH-independent dissolution profile compared with pharmaceutical compositions comprising dasatinib monohydrate. Thus, pharmaceutical compositions comprising dasatinib anhydrous can be used in the treatment of chronic myel...

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Main Authors HOFMANN, Jiri, BARTUNEK, Ales, NOVAK, Martin, SEDMAK, Gregor
Format Patent
LanguageEnglish
French
German
Published 11.01.2023
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Abstract Pharmaceutical compositions comprising dasatinib anhydrous provide an improved, pH-independent dissolution profile compared with pharmaceutical compositions comprising dasatinib monohydrate. Thus, pharmaceutical compositions comprising dasatinib anhydrous can be used in the treatment of chronic myelogenous leukaemia (CML) and/or Philadelphia chromosome positive (Ph+) acute lymphoblastic leukaemia (ALL), especially in subjects having an increased gastric pH and/or in subjects being co-administered with a gastric acid reducing agent.
AbstractList Pharmaceutical compositions comprising dasatinib anhydrous provide an improved, pH-independent dissolution profile compared with pharmaceutical compositions comprising dasatinib monohydrate. Thus, pharmaceutical compositions comprising dasatinib anhydrous can be used in the treatment of chronic myelogenous leukaemia (CML) and/or Philadelphia chromosome positive (Ph+) acute lymphoblastic leukaemia (ALL), especially in subjects having an increased gastric pH and/or in subjects being co-administered with a gastric acid reducing agent.
Author BARTUNEK, Ales
HOFMANN, Jiri
SEDMAK, Gregor
NOVAK, Martin
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DocumentTitleAlternate COMPOSITIONS PHARMACEUTIQUES COMPRENANT DU DASATINIB ANHYDRE ET LEURS UTILISATIONS
PHARMAZEUTISCHE ZUSAMMENSETZUNGEN MIT WASSERFREIEM DASATINIB UND VERWENDUNGEN DAVON
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Snippet Pharmaceutical compositions comprising dasatinib anhydrous provide an improved, pH-independent dissolution profile compared with pharmaceutical compositions...
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MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title PHARMACEUTICAL COMPOSITIONS COMPRISING DASATINIB ANHYDROUS AND USES THEREOF
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