PHARMACEUTICAL COMPOSITIONS COMPRISING DASATINIB ANHYDROUS AND USES THEREOF
Pharmaceutical compositions comprising dasatinib anhydrous provide an improved, pH-independent dissolution profile compared with pharmaceutical compositions comprising dasatinib monohydrate. Thus, pharmaceutical compositions comprising dasatinib anhydrous can be used in the treatment of chronic myel...
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Format | Patent |
Language | English French German |
Published |
11.01.2023
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Abstract | Pharmaceutical compositions comprising dasatinib anhydrous provide an improved, pH-independent dissolution profile compared with pharmaceutical compositions comprising dasatinib monohydrate. Thus, pharmaceutical compositions comprising dasatinib anhydrous can be used in the treatment of chronic myelogenous leukaemia (CML) and/or Philadelphia chromosome positive (Ph+) acute lymphoblastic leukaemia (ALL), especially in subjects having an increased gastric pH and/or in subjects being co-administered with a gastric acid reducing agent. |
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AbstractList | Pharmaceutical compositions comprising dasatinib anhydrous provide an improved, pH-independent dissolution profile compared with pharmaceutical compositions comprising dasatinib monohydrate. Thus, pharmaceutical compositions comprising dasatinib anhydrous can be used in the treatment of chronic myelogenous leukaemia (CML) and/or Philadelphia chromosome positive (Ph+) acute lymphoblastic leukaemia (ALL), especially in subjects having an increased gastric pH and/or in subjects being co-administered with a gastric acid reducing agent. |
Author | BARTUNEK, Ales HOFMANN, Jiri SEDMAK, Gregor NOVAK, Martin |
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DocumentTitleAlternate | COMPOSITIONS PHARMACEUTIQUES COMPRENANT DU DASATINIB ANHYDRE ET LEURS UTILISATIONS PHARMAZEUTISCHE ZUSAMMENSETZUNGEN MIT WASSERFREIEM DASATINIB UND VERWENDUNGEN DAVON |
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Snippet | Pharmaceutical compositions comprising dasatinib anhydrous provide an improved, pH-independent dissolution profile compared with pharmaceutical compositions... |
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Title | PHARMACEUTICAL COMPOSITIONS COMPRISING DASATINIB ANHYDROUS AND USES THEREOF |
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