SUBSTITUTED TETRAHYDROFURANS AS MODULATORS OF SODIUM CHANNELS

Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharm...

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Main Authors SKERRATT, Sarah, THOMSON, Stephen, Andrew, DURRANT, Steven, John, PONTILLO, Joseph, ETXEBARRIA JARDI, Gorka, PINDER, Joanne, Louise, HURLEY, Dennis, James, NEUBERT, Timothy, Donald, GALAN, Bhairavi, HADIDA RUAH, Sara, S, AHMAD, Nadia, CHUDYK, Ewa, Iwona, STAMOS, Dean, VIRANI, Anisa, Nizarali, CARVALHO MEIRELES, Lidio, SHAW, David, Matthew, KNEGTEL, Ronald, Marcellus, PULLIN, Robert, SCHMIDT, Yvonne, BECK, Elizabeth, Mary, WRAY, Christopher
Format Patent
LanguageEnglish
French
German
Published 12.10.2022
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Abstract Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.
AbstractList Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.
Author VIRANI, Anisa, Nizarali
GALAN, Bhairavi
SHAW, David, Matthew
SKERRATT, Sarah
WRAY, Christopher
KNEGTEL, Ronald, Marcellus
HADIDA RUAH, Sara, S
CARVALHO MEIRELES, Lidio
PONTILLO, Joseph
STAMOS, Dean
BECK, Elizabeth, Mary
PULLIN, Robert
THOMSON, Stephen, Andrew
CHUDYK, Ewa, Iwona
ETXEBARRIA JARDI, Gorka
AHMAD, Nadia
NEUBERT, Timothy, Donald
PINDER, Joanne, Louise
HURLEY, Dennis, James
SCHMIDT, Yvonne
DURRANT, Steven, John
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– fullname: PONTILLO, Joseph
– fullname: ETXEBARRIA JARDI, Gorka
– fullname: PINDER, Joanne, Louise
– fullname: HURLEY, Dennis, James
– fullname: NEUBERT, Timothy, Donald
– fullname: GALAN, Bhairavi
– fullname: HADIDA RUAH, Sara, S
– fullname: AHMAD, Nadia
– fullname: CHUDYK, Ewa, Iwona
– fullname: STAMOS, Dean
– fullname: VIRANI, Anisa, Nizarali
– fullname: CARVALHO MEIRELES, Lidio
– fullname: SHAW, David, Matthew
– fullname: KNEGTEL, Ronald, Marcellus
– fullname: PULLIN, Robert
– fullname: SCHMIDT, Yvonne
– fullname: BECK, Elizabeth, Mary
– fullname: WRAY, Christopher
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DocumentTitleAlternate SUBSTITUIERTE TETRAHYDROFURANE ALS MODULATOREN VON NATRIUMKANÄLEN
TÉTRAHYDROFURANES SUBSTITUÉS EN TANT QUE MODULATEURS DE CANAUX SODIQUES
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Snippet Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions...
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SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title SUBSTITUTED TETRAHYDROFURANS AS MODULATORS OF SODIUM CHANNELS
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