CHOLINE SALT FORMS OF AN HIV CAPSID INHIBITOR
The present disclosure relates to choline salts, and crystalline forms thereof, of a compound which is N-((S)-1-(3-(4-chloro-3-(methylsulfonamido)-1-(2,2,2-trifluoroethyl)-1H-indazol-7-yl)-6-(3-methyl-3-(methylsulfonyl)but-1-yn-1-yl)pyridin-2-yl)-2-(3,5-difluorophenyl)ethyl)-2-((3bS,4aR)-5,5-difluor...
Saved in:
| Main Authors | , |
|---|---|
| Format | Patent |
| Language | English French German |
| Published |
21.02.2024
|
| Subjects | |
| Online Access | Get full text |
Cover
Loading…
| Abstract | The present disclosure relates to choline salts, and crystalline forms thereof, of a compound which is N-((S)-1-(3-(4-chloro-3-(methylsulfonamido)-1-(2,2,2-trifluoroethyl)-1H-indazol-7-yl)-6-(3-methyl-3-(methylsulfonyl)but-1-yn-1-yl)pyridin-2-yl)-2-(3,5-difluorophenyl)ethyl)-2-((3bS,4aR)-5,5-difluoro-3-(trifluoromethyl)-3b,4,4a,5-tetrahydro-1H-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl)acetamide, which is useful in the treatment and prevention of a Retroviridae viral infection including an infection caused by the HIV virus. |
|---|---|
| AbstractList | The present disclosure relates to choline salts, and crystalline forms thereof, of a compound which is N-((S)-1-(3-(4-chloro-3-(methylsulfonamido)-1-(2,2,2-trifluoroethyl)-1H-indazol-7-yl)-6-(3-methyl-3-(methylsulfonyl)but-1-yn-1-yl)pyridin-2-yl)-2-(3,5-difluorophenyl)ethyl)-2-((3bS,4aR)-5,5-difluoro-3-(trifluoromethyl)-3b,4,4a,5-tetrahydro-1H-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl)acetamide, which is useful in the treatment and prevention of a Retroviridae viral infection including an infection caused by the HIV virus. |
| Author | HOUSTON, Travis, Lee SHI, Bing |
| Author_xml | – fullname: SHI, Bing – fullname: HOUSTON, Travis, Lee |
| BookMark | eNrjYmDJy89L5WTQdfbw9_H0c1UIdvQJUXDzD_INVvB3U3D0U_DwDFNwdgwI9nRR8PTz8HTyDPEP4mFgTUvMKU7lhdLcDApuriHOHrqpBfnxqcUFicmpeakl8a4BJgYmZpaWJs4GxkQoAQA90iaI |
| ContentType | Patent |
| DBID | EVB |
| DatabaseName | esp@cenet |
| DatabaseTitleList | |
| Database_xml | – sequence: 1 dbid: EVB name: esp@cenet url: http://worldwide.espacenet.com/singleLineSearch?locale=en_EP sourceTypes: Open Access Repository |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine Chemistry Sciences |
| DocumentTitleAlternate | FORMES DE SEL D'UN INHIBITEUR DE CAPSIDE HIV CHOLINSALZFORMEN EINES HIV-CAPSID-INHIBITORS |
| ExternalDocumentID | EP4046994C0 |
| GroupedDBID | EVB |
| ID | FETCH-epo_espacenet_EP4046994C03 |
| IEDL.DBID | EVB |
| IngestDate | Fri Aug 23 06:52:18 EDT 2024 |
| IsOpenAccess | true |
| IsPeerReviewed | false |
| IsScholarly | false |
| Language | English French German |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-epo_espacenet_EP4046994C03 |
| Notes | Application Number: EP20210217553 |
| OpenAccessLink | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240221&DB=EPODOC&CC=EP&NR=4046994C0 |
| ParticipantIDs | epo_espacenet_EP4046994C0 |
| PublicationCentury | 2000 |
| PublicationDate | 20240221 |
| PublicationDateYYYYMMDD | 2024-02-21 |
| PublicationDate_xml | – month: 02 year: 2024 text: 20240221 day: 21 |
| PublicationDecade | 2020 |
| PublicationYear | 2024 |
| RelatedCompanies | Gilead Sciences, Inc |
| RelatedCompanies_xml | – name: Gilead Sciences, Inc |
| Score | 3.52031 |
| Snippet | The present disclosure relates to choline salts, and crystalline forms thereof, of a compound which is... |
| SourceID | epo |
| SourceType | Open Access Repository |
| SubjectTerms | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| Title | CHOLINE SALT FORMS OF AN HIV CAPSID INHIBITOR |
| URI | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240221&DB=EPODOC&locale=&CC=EP&NR=4046994C0 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3NS8MwFH-MKepNp-L8IgfpLWjXbGsPRdq0pRX7wVrHbmNtM9hlDlfx3_cldNOL3kICL8kjv7z88vLyAB7wCI3L5EnQcri0qEy2Tc16YNFar0u02BUz1KvKOBmFb-xlNpx1YLWLhVH_hH6pzxERURXivVH79ebnEstTbyu3j-UKq96fg8L2tJYdS1fBQNc81_az1Eu5xjmWtGRiM8kDLcaR3R_gKXosweBPXRmUsvltUYJTOMxQ2Lo5g45Y9-CY7xKv9eAobv3dWGyhtz0HKn0-UeKT3HktCHK3OCdpQJyEhNGUcCfLI49ESRi5UZFOLoAEfsFDiv3O93Oc-9l-hMYldJH6iysg-gj5GTOWrGYm0yvDXIhaWGbNrHIxXlR6H_p_irn-p-0GTqSyVGi2fgvd5uNT3KFxbcp7pZZv_JV4eg |
| link.rule.ids | 230,309,783,888,25576,76876 |
| linkProvider | European Patent Office |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1LT8MwDLamgRg3GCDGMwfUWwVds609VKhNW7WwPrSWabeqr0m7jIkV8fdxom5wgZuVSIljxbG_OHYAHtCFxm3yVMvFaKnL_LNtWauGulwpVYEWu6SqeFUZhGPvjb4sRosOrHa5MKJO6JcojogaVaK-N-K83vxcYtnibeX2sVhh0_uzmxq21KJjHioYKpJtGU4c2RGTGENKCmcG5ThQpwzR_QF62BOuDM7c4kkpm98WxT2BwxgHWzen0KnXfeix3cdrfTgK2ng3kq3qbc9A5jEfP3RIYk5TgtgtSEjkEjMknj8nzIwT3yZ-6PmWn0azcyCukzJPxnmz_RozJ95zqF5AF6F_fQlEGSM-o-qSVlSjSqlqeV3VulZRvcgneakMYPDnMFf_9N1Dz0uDaYZsv17DMRecSNNWbqDbfHzWt2hom-JOiOgbzih7bQ |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Apatent&rft.title=CHOLINE+SALT+FORMS+OF+AN+HIV+CAPSID+INHIBITOR&rft.inventor=SHI%2C+Bing&rft.inventor=HOUSTON%2C+Travis%2C+Lee&rft.date=2024-02-21&rft.externalDBID=C0&rft.externalDocID=EP4046994C0 |