STAPHYLOCOCCUS PEPTIDES AND METHODS OF USE
Provided herein are immunogenic compositions comprising a Staphylococcus aureus protein A (SpA) variant and a mutant staphylococcal leukocidin subunit polypeptide comprising a LukA polypeptide, a LukB polypeptide, and/or a LukAB dimer polypeptide, wherein the LukA polypeptide, the LukB polypeptide,...
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Format | Patent |
Language | English French German |
Published |
10.08.2022
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Abstract | Provided herein are immunogenic compositions comprising a Staphylococcus aureus protein A (SpA) variant and a mutant staphylococcal leukocidin subunit polypeptide comprising a LukA polypeptide, a LukB polypeptide, and/or a LukAB dimer polypeptide, wherein the LukA polypeptide, the LukB polypeptide, and/or the LukAB dimer polypeptide have one or more amino acid substitutions, deletions, or a combination thereof. |
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AbstractList | Provided herein are immunogenic compositions comprising a Staphylococcus aureus protein A (SpA) variant and a mutant staphylococcal leukocidin subunit polypeptide comprising a LukA polypeptide, a LukB polypeptide, and/or a LukAB dimer polypeptide, wherein the LukA polypeptide, the LukB polypeptide, and/or the LukAB dimer polypeptide have one or more amino acid substitutions, deletions, or a combination thereof. |
Author | SCHNEEWIND, Olaf KIM, Hwan Keun FERNANDEZ, Jeffrey A CHEN, Xinhai SHI, Miaomiao POOLMAN, Jan Theunis MISSIAKAS, Dominique SUN, Yan |
Author_xml | – fullname: KIM, Hwan Keun – fullname: SHI, Miaomiao – fullname: FERNANDEZ, Jeffrey A – fullname: POOLMAN, Jan Theunis – fullname: MISSIAKAS, Dominique – fullname: SUN, Yan – fullname: CHEN, Xinhai – fullname: SCHNEEWIND, Olaf |
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DocumentTitleAlternate | PEPTIDES DE STAPHYLOCOCCUS ET PROCÉDÉS D'UTILISATION STAPHYLOCOCCUS-PEPTIDE UND VERFAHREN ZUR VERWENDUNG |
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RelatedCompanies | The University of Chicago Janssen Vaccines & Prevention B.V |
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Snippet | Provided herein are immunogenic compositions comprising a Staphylococcus aureus protein A (SpA) variant and a mutant staphylococcal leukocidin subunit... |
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SubjectTerms | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
Title | STAPHYLOCOCCUS PEPTIDES AND METHODS OF USE |
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