INHIBITORS OF RECEPTOR INTERACTING PROTEIN KINASE I FOR THE TREATMENT OF DISEASE

Disclosed herein are compounds which inhibit RIPK1, pharmaceutical compositions, and methods of treatment of RIPK1-mediated diseases, such as neurodegenerative disorders, inflammatory disorders, and cancer.

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Main Authors HAMILTON, Matthew, RAY, William, LEWIS, Richard, PFAFFINGER, Dana, REYNA, Naphtali, RAMASWAMY, Suyambu Kesava Vijayan, ALVAREZ, Fernando, CROSS, Jason
Format Patent
LanguageEnglish
French
German
Published 06.09.2023
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Abstract Disclosed herein are compounds which inhibit RIPK1, pharmaceutical compositions, and methods of treatment of RIPK1-mediated diseases, such as neurodegenerative disorders, inflammatory disorders, and cancer.
AbstractList Disclosed herein are compounds which inhibit RIPK1, pharmaceutical compositions, and methods of treatment of RIPK1-mediated diseases, such as neurodegenerative disorders, inflammatory disorders, and cancer.
Author REYNA, Naphtali
RAMASWAMY, Suyambu Kesava Vijayan
ALVAREZ, Fernando
LEWIS, Richard
RAY, William
HAMILTON, Matthew
PFAFFINGER, Dana
CROSS, Jason
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– fullname: LEWIS, Richard
– fullname: PFAFFINGER, Dana
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– fullname: RAMASWAMY, Suyambu Kesava Vijayan
– fullname: ALVAREZ, Fernando
– fullname: CROSS, Jason
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DocumentTitleAlternate INHIBITOREN DER REZEPTOR-INTERAGIERENDEN PROTEINKINASE I ZUR BEHANDLUNG VON KRANKHEITEN
INHIBITEURS DE LA PROTÉINE KINASE I INTERAGISSANT AVEC DES RÉCEPTEURS POUR LE TRAITEMENT D'UNE MALADIE
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Snippet Disclosed herein are compounds which inhibit RIPK1, pharmaceutical compositions, and methods of treatment of RIPK1-mediated diseases, such as neurodegenerative...
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SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title INHIBITORS OF RECEPTOR INTERACTING PROTEIN KINASE I FOR THE TREATMENT OF DISEASE
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