RHO KINASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF

Provided herein are certain inhibitors of ROCK (rho-kinases or rho-associated kinases), which are useful as medicament, for the treatment Huntington's disease in particular.

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Main Authors LEE, Matthew R, BARNES, Michael, DOMINGUEZ, Celia, MAILLARD, Michel C, LADDUWAHETTY, Tammy, LUCKHURST, Christopher A, STOTT, Andrew J, TIERNEY, Jason, HAUGHAN, Alan F
Format Patent
LanguageEnglish
French
German
Published 04.05.2022
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Abstract Provided herein are certain inhibitors of ROCK (rho-kinases or rho-associated kinases), which are useful as medicament, for the treatment Huntington's disease in particular.
AbstractList Provided herein are certain inhibitors of ROCK (rho-kinases or rho-associated kinases), which are useful as medicament, for the treatment Huntington's disease in particular.
Author LADDUWAHETTY, Tammy
LUCKHURST, Christopher A
LEE, Matthew R
DOMINGUEZ, Celia
STOTT, Andrew J
TIERNEY, Jason
MAILLARD, Michel C
BARNES, Michael
HAUGHAN, Alan F
Author_xml – fullname: LEE, Matthew R
– fullname: BARNES, Michael
– fullname: DOMINGUEZ, Celia
– fullname: MAILLARD, Michel C
– fullname: LADDUWAHETTY, Tammy
– fullname: LUCKHURST, Christopher A
– fullname: STOTT, Andrew J
– fullname: TIERNEY, Jason
– fullname: HAUGHAN, Alan F
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DocumentTitleAlternate RHO-KINASEHEMMER SOWIE ZUSAMMENSETZUNGEN UND VERFAHREN ZUR VERWENDUNG DAVON
INHIBITEURS DE LA RHO KINASE ET COMPOSITIONS ET PROCÉDÉS D'UTILISATION DE CEUX-CI
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Snippet Provided herein are certain inhibitors of ROCK (rho-kinases or rho-associated kinases), which are useful as medicament, for the treatment Huntington's disease...
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SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title RHO KINASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF
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