IMPROVED A-BETA PROTOFIBRIL BINDING ANTIBODIES
The present invention relates to the amyloid beta peptide (Aβ) and more specifically to antibodies binding to Aβ protofibrils and their use in therapy and/or prophylactic treatment of Alzheimer's disease and other disorders associated with Aβ protein aggregation. Further the invention may relat...
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| Main Authors | , , |
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| Format | Patent |
| Language | English French German |
| Published |
27.10.2021
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| Subjects | |
| Online Access | Get full text |
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| Abstract | The present invention relates to the amyloid beta peptide (Aβ) and more specifically to antibodies binding to Aβ protofibrils and their use in therapy and/or prophylactic treatment of Alzheimer's disease and other disorders associated with Aβ protein aggregation. Further the invention may relate to diagnosis of such diseases as well as monitoring of disease progression by use of the antibodies of the invention. Further, the invention may relate to veterinary use of the antibodies of the invention. |
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| AbstractList | The present invention relates to the amyloid beta peptide (Aβ) and more specifically to antibodies binding to Aβ protofibrils and their use in therapy and/or prophylactic treatment of Alzheimer's disease and other disorders associated with Aβ protein aggregation. Further the invention may relate to diagnosis of such diseases as well as monitoring of disease progression by use of the antibodies of the invention. Further, the invention may relate to veterinary use of the antibodies of the invention. |
| Author | LAUDON, Hanna SIGVARDSON, Jessica NERELIUS, Charlotte |
| Author_xml | – fullname: SIGVARDSON, Jessica – fullname: NERELIUS, Charlotte – fullname: LAUDON, Hanna |
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| DocumentTitleAlternate | VERBESSERTE A-BETA-PROTOFIBRIL-BINDENDE ANTIKÖRPER ANTICORPS À LIAISON PROTOFIBRILLE A-BÊTA AMÉLIORÉE |
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| PublicationDate | 20211027 |
| PublicationDateYYYYMMDD | 2021-10-27 |
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| PublicationYear | 2021 |
| RelatedCompanies | Eisai R&D Management Co., Ltd BioArctic AB |
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| Snippet | The present invention relates to the amyloid beta peptide (Aβ) and more specifically to antibodies binding to Aβ protofibrils and their use in therapy and/or... |
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| SubjectTerms | CHEMISTRY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING METALLURGY ORGANIC CHEMISTRY PEPTIDES PHYSICS TESTING |
| Title | IMPROVED A-BETA PROTOFIBRIL BINDING ANTIBODIES |
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