DNA POLYMERASE MUTANT SUITED TO NUCLEIC ACID AMPLIFICATION FROM RNA

Provided are: a DNA polymerase mutant having reverse transcriptase activity, the DNA polymerase mutant including a sequence consisting of twelve specific amino acids A1-A12, wherein the DNA polymerase mutant having reverse transcriptase activity is characterized in that the A3 and/or A10 amino acid...

Full description

Saved in:
Bibliographic Details
Main Authors SAITO, Kensuke, AKITOMO, Miwa, UEMORI, Takashi, MATSUMOTO, Hiroyuki
Format Patent
LanguageEnglish
French
German
Published 06.04.2022
Subjects
Online AccessGet full text

Cover

Loading…
More Information
Summary:Provided are: a DNA polymerase mutant having reverse transcriptase activity, the DNA polymerase mutant including a sequence consisting of twelve specific amino acids A1-A12, wherein the DNA polymerase mutant having reverse transcriptase activity is characterized in that the A3 and/or A10 amino acid is substituted by a basic amino acid residue different from that prior to the introduction of mutation; a kit and a composition including the DNA polymerase; a method for producing the DNA polymerase; and a method for modifying an existing DNA polymerase having reverse transcriptase activity.
Bibliography:Application Number: EP20190833322