A RECONSTITUTABLE TEVERELIX-TFA COMPOSITION

The present invention relates to a reconstitutable teverelix-TFA composition having a predefined molar ratio of teverelix to trifluoroacetate which is below the molar ratio required for microcrystal formation. Said composition remains stable during storage e.g. at a temperature around 2-8°C. Upon re...

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Bibliographic Details
Main Authors LARSEN, Finn, POLAND, Guy, BOUTIGNON, François
Format Patent
LanguageEnglish
French
German
Published 12.05.2021
Subjects
BLASTING
DRYING
DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
HEATING
HUMAN NECESSITIES
HYGIENE
LIGHTING
MECHANICAL ENGINEERING
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
WEAPONS
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Summary:The present invention relates to a reconstitutable teverelix-TFA composition having a predefined molar ratio of teverelix to trifluoroacetate which is below the molar ratio required for microcrystal formation. Said composition remains stable during storage e.g. at a temperature around 2-8°C. Upon reconstitution a fixed amount of trifluoroacetate can be added to said composition thereby effectively and simply achieving an exact and desired molar ratio in order to obtain a fluid, milky microcrystalline aqueous teverelix-TFA suspension.
Bibliography:Application Number: EP20190740498