CD3-NEGATIVE CELL POPULATION EXPRESSING CHEMOKINE RECEPTOR AND CELL ADHESION MOLECULE, USE THEREOF, AND METHOD FOR PRODUCING SAME
The present invention relates to an immunocyte having higher cytotoxic activity, and a pharmaceutical composition for NK cell therapies, for which high effect can be expected. The present invention provides a cell population including CCR5-positive, CCR6-positive, CXCR3-positive, and CD3-negative ce...
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Format | Patent |
Language | English French German |
Published |
12.01.2022
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Abstract | The present invention relates to an immunocyte having higher cytotoxic activity, and a pharmaceutical composition for NK cell therapies, for which high effect can be expected. The present invention provides a cell population including CCR5-positive, CCR6-positive, CXCR3-positive, and CD3-negative cells. The present invention provides the cell population, wherein the CCR5-positive, CCR6-positive, CXCR3-positive, and CD3-negative cells further highly express CD11c. The present invention provides a CCR5-positive, CCR6-positive, CXCR3-positive, and CD3-negative cell, which infiltrates into a solid tumor. The present invention also provides a pharmaceutical composition containing such a cell population and a pharmaceutically acceptable additive. The present invention further provides a method for producing the aforementioned cell population. |
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AbstractList | The present invention relates to an immunocyte having higher cytotoxic activity, and a pharmaceutical composition for NK cell therapies, for which high effect can be expected. The present invention provides a cell population including CCR5-positive, CCR6-positive, CXCR3-positive, and CD3-negative cells. The present invention provides the cell population, wherein the CCR5-positive, CCR6-positive, CXCR3-positive, and CD3-negative cells further highly express CD11c. The present invention provides a CCR5-positive, CCR6-positive, CXCR3-positive, and CD3-negative cell, which infiltrates into a solid tumor. The present invention also provides a pharmaceutical composition containing such a cell population and a pharmaceutically acceptable additive. The present invention further provides a method for producing the aforementioned cell population. |
Author | YONEMITSU, Yoshikazu HARADA, Yui |
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DocumentTitleAlternate | CHEMOKIN-REZEPTOR EXPRIMIERENDE CD3-NEGATIVE ZELLPOPULATION UND ZELLADHÄSIONSMOLEKÜL, VERWENDUNG DAVON UND HERSTELLUNGSVERFAHREN DAFÜR POPULATION DE CELLULES CD3 NÉGATIVES EXPRIMANT UN RÉCEPTEUR DE CHIMIOKINE ET UNE MOLÉCULE D'ADHÉRENCE CELLULAIRE, ET APPLICATION AINSI QUE PROCÉDÉ DE FABRICATION ASSOCIÉS |
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RelatedCompanies | GAIA BioMedicine Inc Yonemitsu, Yoshikazu |
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Snippet | The present invention relates to an immunocyte having higher cytotoxic activity, and a pharmaceutical composition for NK cell therapies, for which high effect... |
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SubjectTerms | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE |
Title | CD3-NEGATIVE CELL POPULATION EXPRESSING CHEMOKINE RECEPTOR AND CELL ADHESION MOLECULE, USE THEREOF, AND METHOD FOR PRODUCING SAME |
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