METHOD OF TREATING FIBROTIC DISEASE

• Main Authors: BUCKMAN, Brad Owen, RAJAGOPALAN, P.T. Ravi, IBRAHIM, Prabha
• Format: Patent
• Language: English; French; German
• Published: 17.02.2021
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

Disclosed herein are methods of treating fibrotic disorders by administering compounds selective for CAPN1, CAPN2, and/or CAPN9 such that side effects, off pathway interactions, and/or toxicities are minimized Such methods may, for example, minimize unintended effects of therapeutic compounds by pro...