SUBSTITUTED IMIDAZOLE FORMATE DERIVATIVE AND USE THEREOF
Disclosed is a compound as shown in formula (I), or a stereoisomer thereof, or a pharmaceutically acceptable salt thereof, or a solvate thereof, or a prodrug thereof, or a metabolite thereof, or a deuterated derivative thereof. The compound is a structurally novel substituted imidazole formate deriv...
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Format | Patent |
Language | English French German |
Published |
01.12.2021
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Abstract | Disclosed is a compound as shown in formula (I), or a stereoisomer thereof, or a pharmaceutically acceptable salt thereof, or a solvate thereof, or a prodrug thereof, or a metabolite thereof, or a deuterated derivative thereof. The compound is a structurally novel substituted imidazole formate derivative, belonging to the field of medicinal chemistry. Also disclosed are the use of the substituted imidazole formate derivative in preparing a drug with sedative, hypnotic and/or anesthetic effects, and the use of same in preparing a drug that can control the state of epilepsy. The compound has a good inhibitory effect on the central nervous system, and provides a new option for clinical screening of and/or preparation of a drug with sedative, hypnotic and/or anesthetic effects and controlling the state of epilepsy. |
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AbstractList | Disclosed is a compound as shown in formula (I), or a stereoisomer thereof, or a pharmaceutically acceptable salt thereof, or a solvate thereof, or a prodrug thereof, or a metabolite thereof, or a deuterated derivative thereof. The compound is a structurally novel substituted imidazole formate derivative, belonging to the field of medicinal chemistry. Also disclosed are the use of the substituted imidazole formate derivative in preparing a drug with sedative, hypnotic and/or anesthetic effects, and the use of same in preparing a drug that can control the state of epilepsy. The compound has a good inhibitory effect on the central nervous system, and provides a new option for clinical screening of and/or preparation of a drug with sedative, hypnotic and/or anesthetic effects and controlling the state of epilepsy. |
Author | MA, Haijun WANG, Changhua XIE, Zhenbiao |
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Discipline | Medicine Chemistry Sciences |
DocumentTitleAlternate | SUBSTITUIERTES IMIDAZOLFORMATDERIVAT UND DESSEN VERWENDUNG DÉRIVÉ DE FORMIATE D'IMIDAZOLE SUBSTITUÉ ET UTILISATION ASSOCIÉE |
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Notes | Application Number: EP20190747964 |
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PublicationYear | 2021 |
RelatedCompanies | CHENGDU MFS PHARMA. CO., LTD |
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Snippet | Disclosed is a compound as shown in formula (I), or a stereoisomer thereof, or a pharmaceutically acceptable salt thereof, or a solvate thereof, or a prodrug... |
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SubjectTerms | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
Title | SUBSTITUTED IMIDAZOLE FORMATE DERIVATIVE AND USE THEREOF |
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