A NOVEL DRUG DELIVERY SYSTEM AND METHODS PROVIDING THEREOF

The invention relates to a method for providing a virus-like particle (VLP) derived from John Cunningham virus (JCV), relates to a VLP associated with a cargo, in particular a protein, and a drug delivery system (DDS) obtainable by said method, in particular for crossing the blood brain barrier (BBB...

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Main Authors STAPF, Marcus, SOTNIKOV, Sergey, KOßMANN, Katja Janina, DEMINA, Victoria, MANNINGA, Heiko
Format Patent
LanguageEnglish
French
German
Published 26.10.2022
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Abstract The invention relates to a method for providing a virus-like particle (VLP) derived from John Cunningham virus (JCV), relates to a VLP associated with a cargo, in particular a protein, and a drug delivery system (DDS) obtainable by said method, in particular for crossing the blood brain barrier (BBB), and a VLP containing composition. The method comprises steps of disassembly of VLP into pentamers, inducing the pentamers to aggregate and reassembly into VLP.
AbstractList The invention relates to a method for providing a virus-like particle (VLP) derived from John Cunningham virus (JCV), relates to a VLP associated with a cargo, in particular a protein, and a drug delivery system (DDS) obtainable by said method, in particular for crossing the blood brain barrier (BBB), and a VLP containing composition. The method comprises steps of disassembly of VLP into pentamers, inducing the pentamers to aggregate and reassembly into VLP.
Author STAPF, Marcus
MANNINGA, Heiko
KOßMANN, Katja Janina
SOTNIKOV, Sergey
DEMINA, Victoria
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– fullname: MANNINGA, Heiko
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DocumentTitleAlternate NEUARTIGES ARZNEIMITTELABGABESYSTEM UND VERFAHREN ZUR BEREITSTELLUNG DAVON
NOUVEAU SYSTÈME D'ADMINISTRATION DE MÉDICAMENT ET SES PROCÉDÉS DE FOURNITURE
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Snippet The invention relates to a method for providing a virus-like particle (VLP) derived from John Cunningham virus (JCV), relates to a VLP associated with a cargo,...
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SubjectTerms BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
Title A NOVEL DRUG DELIVERY SYSTEM AND METHODS PROVIDING THEREOF
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