FILLER FOR LIQUID CHROMATOGRAPHY AND COLUMN FOR LIQUID CHROMATOGRAPHY

• Main Authors: KATO, Junya, NAKAJIMA, Naoya, ODA, Natsuki
• Format: Patent
• Language: English; French; German
• Published: 26.05.2021
• Subjects: CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; PERFORMING OPERATIONS; PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL; PHYSICS; SEPARATION; TESTING; THEIR RELEVANT APPARATUS; TRANSPORTING

The present invention relates to a packing material for liquid chromatography, including particles of a copolymer having a monomer unit derived from a (meth)acrylic acid ester and a monomer unit derived from divinylbenzene, wherein a ratio between the monomer unit derived from a (meth)acrylic acid ester and the monomer unit derived from divinylbenzene is 70 mass% to 90 mass%:30 mass% to 10 mass%, wherein the particles each have a sulfo group bonded to a surface thereof and a structure in which the sulfo group is bonded includes a structure represented by the formula (1), where R represents a partial structure derived from the surfaces of the copolymer particles, X represents an oxygen atom or a sulfur atom, and n represents an integer of from 2 to 4, and wherein the particles each include the sulfo group at from 40 µmol/g to 300 µmol/g; and a column using the packing material. The column can be suitably used to analyze proteins, amino acids, and the like, and can be efficiently produced.