BLOOD VESSEL MODEL

The present disclosure provides a blood vessel model including: a pair of channel members, mutually opposing each other, each of which includes an opposing face in which a respective microchannel is formed; and a porous membrane that includes plural through-holes penetrating in a thickness direction...

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Main Authors KAKINUMA, Chihaya, SUNDBACK, Cathryn, A, ITO, Koju, HIKIMOTO, Daichi, MIMA, Shinji, SUEHIRO, Takafumi, NEVILLE, Craig, M
Format Patent
LanguageEnglish
French
German
Published 29.07.2020
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Summary:The present disclosure provides a blood vessel model including: a pair of channel members, mutually opposing each other, each of which includes an opposing face in which a respective microchannel is formed; and a porous membrane that includes plural through-holes penetrating in a thickness direction, that is disposed between the opposing faces of the pair of channel members, and that partitions between the microchannels, wherein the porous membrane is provided with a vascular endothelial cell layer so as to cover one face facing one of the microchannels, an average opening diameter of the through-holes is from 1 μιη to 20 μm, and an opening coverage ratio of the through-holes is from 30% to 70%.
Bibliography:Application Number: EP20180813126