QUINAZOLINES AS POTASSIUM ION CHANNEL INHIBITORS
Pharmaceutical compositions for oral administration comprising a compound of formula (lb) or (Ic) or an enantiomer, diastereomer, tautomer, or salt thereof, and a pharmaceutically acceptable vehicle or diluent:wherein X, Y, Z, R13a - d, R13a-2-d-2and R25are described herein. The compounds are useful...
Saved in:
Main Authors | , , , , , , , , |
---|---|
Format | Patent |
Language | English French German |
Published |
27.10.2021
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | Pharmaceutical compositions for oral administration comprising a compound of formula (lb) or (Ic) or an enantiomer, diastereomer, tautomer, or salt thereof, and a pharmaceutically acceptable vehicle or diluent:wherein X, Y, Z, R13a - d, R13a-2-d-2and R25are described herein. The compounds are useful as inhibitors of potassium channel function and in the treatment and prevention of arrhythmia, IKur-associated disorders, and other disorders mediated by ion channel function. |
---|---|
AbstractList | Pharmaceutical compositions for oral administration comprising a compound of formula (lb) or (Ic) or an enantiomer, diastereomer, tautomer, or salt thereof, and a pharmaceutically acceptable vehicle or diluent:wherein X, Y, Z, R13a - d, R13a-2-d-2and R25are described herein. The compounds are useful as inhibitors of potassium channel function and in the treatment and prevention of arrhythmia, IKur-associated disorders, and other disorders mediated by ion channel function. |
Author | GUNAGA, Prashantha LLOYD, John JIANG, Ji FINLAY, Heather NEELS, James DHONDI, Naveen Kumar JOHNSON, James A BANERJEE, Abhisek ADISECHAN, Ashok Kumar |
Author_xml | – fullname: NEELS, James – fullname: LLOYD, John – fullname: BANERJEE, Abhisek – fullname: JOHNSON, James A – fullname: DHONDI, Naveen Kumar – fullname: JIANG, Ji – fullname: GUNAGA, Prashantha – fullname: ADISECHAN, Ashok Kumar – fullname: FINLAY, Heather |
BookMark | eNrjYmDJy89L5WQwCAz19HOM8vfx9HMNVnAMVgjwD3EMDvYM9VXw9PdTcPZw9PNz9VHw9PPwdPIM8Q8K5mFgTUvMKU7lhdLcDApuriHOHrqpBfnxqcUFicmpeakl8a4BxqbmpkYWFk6GxkQoAQD62ygA |
ContentType | Patent |
DBID | EVB |
DatabaseName | esp@cenet |
DatabaseTitleList | |
Database_xml | – sequence: 1 dbid: EVB name: esp@cenet url: http://worldwide.espacenet.com/singleLineSearch?locale=en_EP sourceTypes: Open Access Repository |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Medicine Chemistry Sciences |
DocumentTitleAlternate | CHINAZOLINE ALS KALIUMIONENKANALHEMMER QUINAZOLINES EN TANT QU'INHIBITEURS DU CANAL IONIQUE DU POTASSIUM |
ExternalDocumentID | EP3575288B1 |
GroupedDBID | EVB |
ID | FETCH-epo_espacenet_EP3575288B13 |
IEDL.DBID | EVB |
IngestDate | Fri Jul 19 14:19:51 EDT 2024 |
IsOpenAccess | true |
IsPeerReviewed | false |
IsScholarly | false |
Language | English French German |
LinkModel | DirectLink |
MergedId | FETCHMERGED-epo_espacenet_EP3575288B13 |
Notes | Application Number: EP20190186129 |
OpenAccessLink | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20211027&DB=EPODOC&CC=EP&NR=3575288B1 |
ParticipantIDs | epo_espacenet_EP3575288B1 |
PublicationCentury | 2000 |
PublicationDate | 20211027 |
PublicationDateYYYYMMDD | 2021-10-27 |
PublicationDate_xml | – month: 10 year: 2021 text: 20211027 day: 27 |
PublicationDecade | 2020 |
PublicationYear | 2021 |
RelatedCompanies | Bristol-Myers Squibb Company |
RelatedCompanies_xml | – name: Bristol-Myers Squibb Company |
Score | 3.3601096 |
Snippet | Pharmaceutical compositions for oral administration comprising a compound of formula (lb) or (Ic) or an enantiomer, diastereomer, tautomer, or salt thereof,... |
SourceID | epo |
SourceType | Open Access Repository |
SubjectTerms | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
Title | QUINAZOLINES AS POTASSIUM ION CHANNEL INHIBITORS |
URI | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20211027&DB=EPODOC&locale=&CC=EP&NR=3575288B1 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3dS8MwED_GFPVNp-L8Ig_St-KWpB97GNKv0crW1q2T4ctougb2Moer-O97Kdv0Rd-OBC7JwX38ktwdwIMlC8somNS57HCdL0yqC4uaupBdlpu24N36b84oNsMpf54ZswYsd7kwdZ3Qr7o4ImpUgfpe1fZ6_XOJ5dd_KzePYolD70-DrO9rW3Ss0Ay1NN_tB2niJ57meUhp8bjPMCyhtu0iUDpQUbQqsx-8uiopZf3bowxO4TBFZqvqDBrlqgXH3q7xWguORtv3biS3qrc5h87LNIqdt2So2mQQZ0LSJHPQFE5HBM0h8UInjoMhieIwcqMsGU8ugAyCzAt1XHq-P-Y8SPebZJfQRPRfXgGRTNoGZ6XsyZwzKno9WYq8sKlli4XJ8za0_2Rz_c_cDZwoeSkzTK1baFYfn-Ud-tdK3NeS-QYuLHsr |
link.rule.ids | 230,309,786,891,25594,76906 |
linkProvider | European Patent Office |
linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfR1NT8Iw9IWgEW-KGsGvHsxui9CWdRyI2RfZlH0IwxAvZB1rwgWJzPj3bRdAL3p7aZPX15e8r_Z9ANwzkbNeToRORYfqdGFgnTNs6Fx0SWaYnHar3JwwMvwpfZr1ZjVY7mphqj6hX1VzRClRuZT3stLX659HLLfKrdw88KVcen8cpgNX20bHKprBTHPtgZfEbuxojiMhLRoPiHRLsGnaMlA6YKo5r_KcXm1VlLL-bVGGJ3CYSGSr8hRqxaoJDWc3eK0JR-H2v1uCW9HbnEHnZRpE1ls8UmMykDVBSZxaUhVOQyTVIXJ8K4q8EQoiP7CDNB5PzgENvdTxdXn0fH_NuZfsiSQXUJfRf3EJSBBh9igpRF9klGDe74uCZ7mJmckXBs1a0PoTTfufvTto-Gk4mkuqn6_gWPFOqWTMrqFefnwWN9LWlvy24tI3GPl-GA |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Apatent&rft.title=QUINAZOLINES+AS+POTASSIUM+ION+CHANNEL+INHIBITORS&rft.inventor=NEELS%2C+James&rft.inventor=LLOYD%2C+John&rft.inventor=BANERJEE%2C+Abhisek&rft.inventor=JOHNSON%2C+James+A&rft.inventor=DHONDI%2C+Naveen+Kumar&rft.inventor=JIANG%2C+Ji&rft.inventor=GUNAGA%2C+Prashantha&rft.inventor=ADISECHAN%2C+Ashok+Kumar&rft.inventor=FINLAY%2C+Heather&rft.date=2021-10-27&rft.externalDBID=B1&rft.externalDocID=EP3575288B1 |